Results 61 to 70 of about 50,978 (164)

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Anti-Niemann Pick C1 Single-Stranded Oligonucleotides with Locked Nucleic Acids Potently Reduce Ebola Virus Infection In Vitro

Molecular Therapy: Nucleic Acids, 2019
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus.
Anne Sadewasser, Erik Dietzel, Sven Michel, Michael Klüver, Markus Helfer, Tamara Thelemann, Richard Klar, Markus Eickmann, Stephan Becker, Frank Jaschinski   +9 more
doaj   +1 more source

Assessment of Environmental Contamination and Environmental Decontamination Practices within an Ebola Holding Unit, Freetown, Sierra Leone. [PDF]

PLoS ONE, 2015
Evidence to inform decontamination practices at Ebola holding units (EHUs) and treatment centres is lacking. We conducted an audit of decontamination procedures inside Connaught Hospital EHU in Freetown, Sierra Leone, by assessing environmental swab ...
Daniel Youkee, Colin S Brown, Paul Lilburn, Nandini Shetty, Tim Brooks, Andrew Simpson, Neil Bentley, Marta Lado, Thaim B Kamara, Naomi F Walker, Oliver Johnson   +10 more
doaj   +1 more source

Do Mobile Phone Surveys Supplement Other Mortality Surveillance Methods? Results From a National Study in Bangladesh

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives To test whether mobile phone surveys conducted remotely might generate data on deaths that are not covered by mortality surveillance systems established in laboratories and health facilities, or in institutions involved in the post‐mortem management of corpses (e.g., morgues, cemeteries).
Aashish Gupta, Gulam Muhammed Al Kibria, Tahsin Shahrin Khan, Chandra Nirod Saha, Farzana Islam Khan, Alain Labrique, Tahmina Shirin, Mohan Diwakar, Georges Reniers, Iqbal Ansary Khan, Dustin G. Gibson, Stephane Helleringer   +11 more
wiley   +1 more source

Rapid Decision Algorithm for Patient Triage during Ebola Outbreaks

Emerging Infectious Diseases
The low specificity of Ebola virus disease clinical signs increases the risk for nosocomial transmission to patients and healthcare workers during outbreaks.
Denis-Luc Ardiet, Justus Nsio, Gaston Komanda, Rebecca M. Coulborn, Emmanuel Grellety, Francesco Grandesso, Richard Kitenge, Dolla L. Ngwanga, Bibiche Matady, Guyguy Manangama, Mathias Mossoko, John K. Ngwama, Placide Mbala, Francisco Luquero, Klaudia Porten, Steve Ahuka-Mundeke   +15 more
doaj   +1 more source

Impacts of the One Big Beautiful Bill Act on African Public Health Systems

Public Health Challenges, Volume 5, Issue 3, September 2026.
ABSTRACT The enactment of the One Big Beautiful Bill Act (OBBBA) in July 2025 represents a fundamental shift in United States global health financing, with significant implications for African public health systems. For more than three decades, US development assistance for health particularly through initiatives such as the President's Emergency Plan ...
Majani Edward, Jusu Musa, Mlemile Stephen, Sam Soko Bundu, Caroline Nakasita Alex, Ameh Wisdom Owoicho, Naima Mbwana   +6 more
wiley   +1 more source

IN VITRO DIAGNOSIS FOR EBOLA VIRUS DISEASE. A COMPARISON OF CURRENT TECHNIQUES AND DIAGNOSTIC ASSAYS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Ebola virus disease is dangerous viral infection, occurring in the form of hemorrhagic fever, characterized by acute clinical symptoms and high mortality rate due to multiple organ failure.
A. O. Sementsova, V. G. Dedkov, V. A. Ternovoy, E. V. Chub, S. A. Pyankov, A. P. Agafonov, R. A. Maksyutov, V. V. Maleev, A. Yu. Popova   +8 more
doaj   +1 more source

A Novel Ebola Virus VP40 Matrix Protein-Based Screening for Identification of Novel Candidate Medical Countermeasures

Viruses, 2020
Filoviruses, such as Ebola virus and Marburg virus, are of significant human health concern. From 2013 to 2016, Ebola virus caused 11,323 fatalities in Western Africa.
Ryan P. Bennett, Courtney L. Finch, Elena N. Postnikova, Ryan A. Stewart, Yingyun Cai, Shuiqing Yu, Janie Liang, Julie Dyall, Jason D. Salter, Harold C. Smith, Jens H. Kuhn   +10 more
doaj   +1 more source

The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures

Reviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria, Francesco Branda, Giancarlo Ceccarelli, Fabio Scarpa, Massimo Ciccozzi, Alessandro Russo   +5 more
wiley   +1 more source

Ebinformatics: Ebola fuzzy informatics systems on the diagnosis, prediction and recommendation of appropriate treatments for Ebola virus disease (EVD)

Informatics in Medicine Unlocked, 2016
Ebola Virus Disease (EVD) also known as the Ebola hemorrhagic fever is a very deadly infectious disease to humankind. Therefore, a safer and complementary method of diagnosis is to employ the use of an expert system in order to initiate a platform for ...
Olugbenga Oluwagbemi, Folakemi Oluwagbemi, Oluyemi Abimbola   +2 more
doaj   +1 more source