Results 81 to 90 of about 50,978 (164)

Post-exposure treatment of Ebola virus using passive immunotherapy: proposal for a new strategy

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background Better treatments are urgently needed for the management of Ebola virus epidemics in Equatorial Africa. Methods We conducted a systematic review of the literature on the use of passive immunotherapy for the treatment or prevention of Ebola ...
Jean-Philippe Chippaux, Leslie V Boyer, Alejandro Alagón   +2 more
doaj   +1 more source

Comment on ‘Comparing specificity and seroconversion sensitivity among major blood screening assays for human immunodeficiency virus and viral hepatitis’

Vox Sanguinis, EarlyView.
Ramune Sepetiene, Mohamed Ali, Guillermo Orjuela, Ted Kieffer, Ellen Ollson, Axel Stover, Jason Kang   +6 more
wiley   +1 more source

Exosome‐Mediated Delivery of PROTACs for Targeted Protein Degradation in Cancer, Neurodegenerative, Infectious, and Inflammatory Diseases

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh, Rumpa Banerjee, Hailah M. Almohaimeed, Amany I. Almars, Tahani Ahmad ALMatrafi, Fayez M. Saleh, Zuhair M. Mohammedsaleh, Kranti Kiran Reddy Ealla, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Identification and Optimization of a Truncated Hs‐1‐Derived Antimicrobial Peptide for Enhanced Broad‐Spectrum Antiviral Activity

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Can a shorter peptide be a better antiviral? Structure‐guided optimization of the amphibian peptide Hs‐1 reveals a minimal α‐helical core that, after terminal modification, displays enhanced stability and submicromolar broad‐spectrum activity against enveloped viruses while maintaining a favorable safety profile. Antimicrobial peptides (AMPs) represent
Carla Zannella, Annalisa Chianese, Rosa Giugliano, Roberta Della Marca, Alessandra Monti, Martina Dragone, Gaetano Malgieri, Nunzianna Doti, Carla Isernia, Anna De Filippis, Massimiliano Galdiero   +10 more
wiley   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Ebola virus disease and breastfeeding [PDF]

The Lancet, 2020
Anna E, Thorson, Megan, Foeller, Pura, Rayco-Solon, Zita Weise, Prinzo, João Paulo, Souza, Juan Pablo, Peña-Rosas   +5 more
openaire   +2 more sources

One month follow up of a neonate born to a mother who survived Ebola virus disease during pregnancy: a case report in the Democratic Republic of Congo

BMC Pediatrics, 2019
Background The authors report a 1 month follow up of a neonate described as “miracle baby” because she was born Ebola virus disease-free and survived after her mother was infected with Ebola virus during the third trimester of pregnancy.
N. Kasereka Baraka, Mupenzi Mumbere, Evie Ndombe   +2 more
doaj   +1 more source

Characterization of atypical Ebola virus disease in ferrets. [PDF]

PLoS Pathog
Cao W, He S, Schulz H, Wight J, Chan M, Emeterio K, Liu G, Audet J, Tierney K, Azaransky K, Frost K, Gee L, McQueen P, Chong P, Sulkosky SB, Booth S, Westmacott G, Saphire EO, Zeng X, Banadyga L.   +19 more
europepmc   +1 more source

Ebola Virus Disease Preparedness in Subnational Health Systems: A Readiness Assessment of Jinja District, Uganda. [PDF]

J Trop Med
Oposhia J, Kungu JM, Nantamu PD, Namayanja J, Okuyo CAB, Mulowoza M, Kabali K, Edson K, Olupot-Olupot P.   +8 more
europepmc   +1 more source

Small molecule drug discovery for Ebola virus disease. [PDF]

RSC Med Chem
Durante D, Murugesh V, Kalanquin T, Gaisina IN, Rong L, Moore TW.   +5 more
europepmc   +1 more source