Results 81 to 90 of about 6,074,393 (210)

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

Immunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton, Bernadette M. Saunders   +1 more
wiley   +1 more source

EBOLA

Zdravniški Vestnik, 2014
The ongoing outbreak of Ebola virus disease is by far the largest in  the history of Ebola virus since its initial description in 1976. Apart from dramatic increase of detected cases in the current outbreak of Ebola virus disease in West Africa, there ...
Tadeja Kotar
doaj  

Assessment of Environmental Contamination and Environmental Decontamination Practices within an Ebola Holding Unit, Freetown, Sierra Leone. [PDF]

PLoS ONE, 2015
Evidence to inform decontamination practices at Ebola holding units (EHUs) and treatment centres is lacking. We conducted an audit of decontamination procedures inside Connaught Hospital EHU in Freetown, Sierra Leone, by assessing environmental swab ...
Daniel Youkee, Colin S Brown, Paul Lilburn, Nandini Shetty, Tim Brooks, Andrew Simpson, Neil Bentley, Marta Lado, Thaim B Kamara, Naomi F Walker, Oliver Johnson   +10 more
doaj   +1 more source

Imported viral haemorrhagic fever with a potential for person-to-person transmission: review and recommendations for initial management of a suspected case in Belgium.

, 2002
Viral haemorrhagic fevers are caused by a wide range of viruses. There are 4 types of viruses well known to spread from person to person and able to cause nosocomial outbreaks with a high case fatality rate: an arenavirus (Lassa fever and more ...
Borchert, M., Moreau, M, Borchert, M, Colebunders, R, Moreau, M., Van Esbroeck, M., Van Esbroeck, M, Colebunders, R.   +7 more
core   +1 more source

Time, place, person: Field epidemiology as a political practice

Medical Anthropology Quarterly, EarlyView.
Abstract Five years after the end of the Ebola epidemic, a district in Sierra Leone received a measles alert. This article tells the story of the epidemic that followed and the response that was mounted in the context of the new global epidemic preparedness and biosecurity paradigms that govern the management of health emergencies.
Luisa Enria
wiley   +1 more source

Rapid Decision Algorithm for Patient Triage during Ebola Outbreaks

Emerging Infectious Diseases
The low specificity of Ebola virus disease clinical signs increases the risk for nosocomial transmission to patients and healthcare workers during outbreaks.
Denis-Luc Ardiet, Justus Nsio, Gaston Komanda, Rebecca M. Coulborn, Emmanuel Grellety, Francesco Grandesso, Richard Kitenge, Dolla L. Ngwanga, Bibiche Matady, Guyguy Manangama, Mathias Mossoko, John K. Ngwama, Placide Mbala, Francisco Luquero, Klaudia Porten, Steve Ahuka-Mundeke   +15 more
doaj   +1 more source

Anti-Niemann Pick C1 Single-Stranded Oligonucleotides with Locked Nucleic Acids Potently Reduce Ebola Virus Infection In Vitro

Molecular Therapy: Nucleic Acids, 2019
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus.
Anne Sadewasser, Erik Dietzel, Sven Michel, Michael Klüver, Markus Helfer, Tamara Thelemann, Richard Klar, Markus Eickmann, Stephan Becker, Frank Jaschinski   +9 more
doaj   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

A Novel Ebola Virus VP40 Matrix Protein-Based Screening for Identification of Novel Candidate Medical Countermeasures

Viruses, 2020
Filoviruses, such as Ebola virus and Marburg virus, are of significant human health concern. From 2013 to 2016, Ebola virus caused 11,323 fatalities in Western Africa.
Ryan P. Bennett, Courtney L. Finch, Elena N. Postnikova, Ryan A. Stewart, Yingyun Cai, Shuiqing Yu, Janie Liang, Julie Dyall, Jason D. Salter, Harold C. Smith, Jens H. Kuhn   +10 more
doaj   +1 more source

Ebinformatics: Ebola fuzzy informatics systems on the diagnosis, prediction and recommendation of appropriate treatments for Ebola virus disease (EVD)

Informatics in Medicine Unlocked, 2016
Ebola Virus Disease (EVD) also known as the Ebola hemorrhagic fever is a very deadly infectious disease to humankind. Therefore, a safer and complementary method of diagnosis is to employ the use of an expert system in order to initiate a platform for ...
Olugbenga Oluwagbemi, Folakemi Oluwagbemi, Oluyemi Abimbola   +2 more
doaj   +1 more source