Results 141 to 150 of about 12,455 (266)

Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form

open access: yesCell Reports, 2021
Summary: The Ebola virus matrix protein VP40 forms distinct structures linked to distinct functions in the virus life cycle. Dimeric VP40 is a structural protein associated with virus assembly, while octameric, ring-shaped VP40 is associated with ...
Sara Landeras-Bueno   +8 more
doaj  

Risk assessment of Ebola Reston virus in humans in the Philippines

open access: yesWestern Pacific Surveillance and Response, 2019
Objective: There have been five documented outbreaks of Ebola Reston virus (RESTV) in animals epidemiologically linked to the Philippines. This assessment was conducted to determine the risk of RESTV occurring in humans in the Philippines and its ...
Johnette A Peñas   +4 more
doaj   +1 more source

Workshop on mobile laboratories deployed in the Ebola outbreak in West-Africa 2014-2015 [PDF]

open access: yes, 2016
First paragraph: Ebola virus disease (EVD) is a haemorrhagic fever caused by Ebola virus (EBOV) with high infectivity and mortality. EBOV is an enveloped, single-stranded, and negative-sense RNA virus belonging to the Filoviridae family.
Faye, Oumar   +4 more
core  

A cytomegalovirus-based vaccine provides long-lasting protection against lethal Ebola virus challenge after a single dose [PDF]

open access: yes, 2017
This is the author accepted manuscript. The final version is available fromElsevier via the DOI in this record.Ebola virus (Zaire ebolavirus; EBOV) is a highly lethal hemorrhagic disease virus that most recently was responsible for two independent 2014 ...
Ball, S   +9 more
core   +1 more source

An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures

open access: yesViruses, 2012
The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
doaj   +1 more source

Ebola Virus Disease in Domestic and Wild Animals: A Review [PDF]

open access: yes, 2016
Ebola virus disease (formerly Ebola hemorrhagic fever) is an acute viral syndrome that presents with fever and an ensuing bleeding diathesis that is marked by high mortality in human and nonhuman primates.
Hambese, Hailu
core   +1 more source

A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

open access: yesmBio, 2019
Ebola virus (EBOV) causes highly lethal disease outbreaks against which no FDA-approved countermeasures are available. Although many host factors exploited by EBOV for cell entry have been identified, including host cell surface phosphatidylserine ...
J. Maximilian Fels   +4 more
doaj   +1 more source

Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014

open access: yesViruses, 2014
In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa.
Jens H. Kuhn   +43 more
doaj   +1 more source

Potential Vaccines and Post-Exposure Treatments for Filovirus Infections

open access: yesViruses, 2012
Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger   +6 more
doaj   +1 more source

Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries [PDF]

open access: yes, 2014
There is growing concern in Sub-Saharan Africa about the spread of the Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, and the public health burden that it ensues.
Emmanuel Ugwu   +2 more
core   +3 more sources

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