Results 141 to 150 of about 12,943 (270)

Endoplasmic reticulum stress in diseases

MedComm, Volume 5, Issue 9, September 2024.
The endoplasmic reticulum (ER) serves as a vital organelle in eukaryotic cells, performing essential roles such as protein folding, modification, and trafficking, lipid biosynthesis, and calcium regulation. Various conditions may disrupt ER function, potentially leading to the accumulation of unfolded and misfolded proteins, and triggering ER stress ...
Yingying Liu, Chunling Xu, Renjun Gu, Ruiqin Han, Ziyun Li, Xianrong Xu   +5 more
wiley   +1 more source

RIG-I activation inhibits ebolavirus replication

Virology, 2009
Hemorrhagic fever viruses are associated with rapidly progressing severe disease with high case fatality, making them of public health and biothreat importance. Effective antivirals are not available for most of the members of this diverse group of viruses. A broad spectrum strategy for antiviral development would be very advantageous. Perhaps the most
Thomas G. Ksiazek, Takashi Fujita, Stuart T. Nichol, Christina F. Spiropoulou, Suryaprakash Sambhara, Pierre E. Rollin, Shivaprakash Gangappa, César G. Albariño, Melissa B. Pearce, Priya Ranjan, Tara K. Sealy   +10 more
openaire   +3 more sources

Ebolavirus:

Revista Gestão & Saúde, 2015
O atual surto de ebola tem devastado centenas de vidas, preocupando a comunidade cientifica devido à alta letalidade e difícil controle. Objetivamos observar quais os principais desafios para o controle do vírus e entender a importância de uma gestão ...
Rachid Figueirôa Souza, Aline Rafaela da Silva Rodrigues Machado, Julie Massayo Maeda Oda, Odanir Garcia Guerra, Alex Martins Machado   +4 more
doaj  

Reston Ebolavirus Antibodies in Bats, the Philippines

Emerging Infectious Diseases, 2011
Reston Ebolavirus Antibodies in Bats, the PhilippinesPara el editor: Los filovirus causan fiebre hemorrágica altamente letal en humanos y primates no humanos, a excepción del Reston Ebolavirus (REBOV), que causa fiebre hemorrágica severa en macacos (1,2). Las epizootias de REBOV entre macacos cynomolgus ocurrieron en 1989, 1990, 1992 y 1996 (2) y entre
Hikaru Fujii, Shigeru Kyuwa, Joseph S. Masangkay, Naoya Ueda, Yoshiyuki Ishii, Phillip A. Alviola, Satoshi Taniguchi, Satoshi Taniguchi, Shigeru Morikawa, Yasuhiro Yoshikawa, Tetsuya Mizutani, Koichiro Iha, Koichiro Iha, Tsutomu Omatsu, Masayuki Saijo, Shumpei Watanabe, Shumpei Watanabe, Ichiro Kurane, Shuetsu Fukushi, Tetsuro Ikegami, Hiroomi Akashi   +20 more
openaire   +3 more sources

Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection. [PDF]

, 2016
Ebolaviruses pose significant public health problems due to their high lethality, unpredictable emergence, and localization to the poorest areas of the world.
A Groseth, A Marzi, A Marzi, AA Murphy, AA Rizvanov, AC Shurtleff, AE Anoh, AJ Redwood, C Genton, CF Hung, D Falzarano, D Malouli, D Moro, DA Stanley, DE Swayne, DM Pigott, DS Reed, E Nakayama, EM Leroy, G Sequar, G Xu, H Feldmann, J Alexander, J Delrieu, JP Bilello, JS Richardson, L Song, LJ Reed, LN Farroway, M Bermejo, NJ Sullivan, NJ Sullivan, NJ Sullivan, NT Pande, P Mahl, S Murthy, SA Ross, SB Boppana, SG Hansen, SG Hansen, SG Hansen, SG Hansen, SG Hansen, SG Hansen, SM Jones, SM Kaech, TW Geisbert, VE Volchkov, WL Chang, X Qiu, X Qiu, Y Tsuda, Y Tsuda   +52 more
core   +2 more sources

Human and murine IFIT1 proteins do not restrict infection of negative-sense RNA viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae families [PDF]

, 2015
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amarasinghe, Gaya, Boon, Adrianus C.M., Brien, James D, Diamond, Michael S, Ebihara, Hideki, Liu, Gai, Mühlberger, Elke, Olejnik, Judith, Pinto, Amelia K, Proença-Módena, José Luiz, Szretter, Kristy J, White, James P, Williams, Graham D   +12 more
core   +3 more sources

Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa. [PDF]

, 2020
Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus ...
Amara, Emmanuel, Amman, Brian R, Bairoh, Fatmata V, Bakarr, Ibrahim A, Bangura, Abdulai A, Bangura, Camilla, Bangura, Doris, Bangura, James, Belaganahalli, Manjunatha, Bird, Brian H, Chow, Andrew, Conteh, Immah, Coomber, Moinya, Dhanota, Jasjeet, Edwin, Lavalie, Foday, Ibrahim, Gbakima, Aiah A, Gibson, Alexandra, Goldstein, Tracey, Graziano, James, Guetiya Wadoum, Raoul Emeric, Jambai, Amara, Johnny, Jonathan, Kamanda, Emmanuel S, Kamara, Sorie M, Kanu, Marilyn, Kanu, Osman, Kargbo, Dickson, Koroma, Alusine H, Lebbie, Aiah, Lungai, Victor, Mazet, Jonna AK, Mereweather-Thompson, Vanessa, Musa, Jonathan, Nichol, Stuart T, Ontiveros, Victoria, Osborne, Augustus, Patel, Ketan, Robert, Willie, Saidu, Emmanuel, Schuh, Amy J, Sealy, Tara K, Singh, Tushar, Taboy, Celine H, Towner, Jonathan S, Tremeau-Bravard, Alexandre, Turay, Joseph, Turay, Mohamed, Wadsworth, Richard, Williams, Samuel Maxwell Tom   +49 more
core  

Estimating the reproduction number of Ebola virus (EBOV) during the 2014 outbreak in West Africa [PDF]

, 2014
The 2014 Ebola virus (EBOV) outbreak in West Africa is the largest outbreak of the genus Ebolavirus to date. To better understand the spread of infection in the affected countries, it is crucial to know the number of secondary cases generated by an ...
Althaus, Christian L.
core   +2 more sources

Risk assessment of Ebola Reston virus in humans in the Philippines

Western Pacific Surveillance and Response, 2019
Objective: There have been five documented outbreaks of Ebola Reston virus (RESTV) in animals epidemiologically linked to the Philippines. This assessment was conducted to determine the risk of RESTV occurring in humans in the Philippines and its ...
Johnette A Peñas, Mary Elizabeth Miranda, Vikki Carr de los Reyes, Ma. Nemia L Sucaldito, Rio L Magpantay   +4 more
doaj   +1 more source

A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

mBio, 2019
Ebola virus (EBOV) causes highly lethal disease outbreaks against which no FDA-approved countermeasures are available. Although many host factors exploited by EBOV for cell entry have been identified, including host cell surface phosphatidylserine ...
J. Maximilian Fels, Jennifer S. Spence, Robert H. Bortz, Zachary A. Bornholdt, Kartik Chandran   +4 more
doaj   +1 more source