Anopheles gambiae blood feeding Initiates an anticipatory defense response to plasmodium berghei
Mosquitoes have potent innate defense mechanisms that protect them from infection by diverse pathogens. Much remains unknown about how different pathogens are sensed and specific responses triggered.
Christophides, GK +2 more
core +1 more source
Proteomic identification of PKC-mediated expression of 20E-induced protein in Drosophila melanogaster [PDF]
Ecdysone receptor (EcR) and its heterodimeric partner, ultraspiracle protein (USP), are nuclear receptors that mediate the action of the insect molting hormone 20-hydroxyecdysone (20E). There is evidence that the activity of both receptors is affected by
An, Shiheng +4 more
core +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract Interactions between developing embryos and a multitude of environmental factors (e.g. climate, nutrition, social cues, stress and anthropogenic contaminants) underlie adaptive and non‐adaptive developmental plasticity and carry broad implications across ecological ...
Benjamin B. Parrott, Samantha L. Bock
wiley +1 more source
Azadirachtin disrupts ecdysone signaling and alters sand fly immunity
Background Leishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects’s immune response.
Cecilia Stahl Vieira +4 more
doaj +1 more source
Monitoring resistance of Cydia pomonella (L.) Spanish field populations to new chemical insecticides and the mechanisms involved [PDF]
BACKGROUND: A widespread resistance of Cydia pomonella to organophosphates was demonstrated in populations from the Spanish Ebro Valley area that showed high levels of enzymatic detoxification.
Avilla Hernández, Jesús +2 more
core +3 more sources
APPi: A Multiscale Qualitative–Quantitative Insecticide‐Likeness Evaluation Platform and Application
An Agrochem Predictive Platform for Insecticide‐likeness: From Qualitative Rules to Quantitative Modeling and Visualization. ABSTRACT According to the Food and Agriculture Organization of the United Nations (FAO), pests reduce global crop production by 14% annually. The growing challenge of pest resistance, coupled with the relatively low success rates
Jia‐lin Cui +7 more
wiley +1 more source
Developmental Expression of \u3cem\u3eDrop-Dead\u3c/em\u3e is Required for Early Adult Survival and Normal Body Mass in \u3cem\u3eDrosophila melanogaster\u3c/em\u3e [PDF]
In Drosophila melanogaster, mutations in the gene drop-dead (drd) result in early adult lethality, with flies dying within 2 weeks of eclosion. Additional phenotypes include neurodegeneration, tracheal defects, starvation, reduced body mass, and female ...
Blumenthal, Edward M +1 more
core +1 more source
Dynamic eIF3‐S6 Phase Separation Switch Instructed by m6A Modification Drives the Molting of Locusts
This research reveals that reduced m6A modifications during insect molting trigger liquid–liquid phase separation (LLPS) of the m6A reader eIF3‐S6, which binds and stabilizes key molting mRNAs, including EcR and Cht10. Disrupting m6A or LLPS causes cuticle remodeling defects and molting failure, highlighting the synergistic control of gene expression ...
Zhihao Hu +8 more
wiley +1 more source
We assessed how an acute heat shock event experienced at two different points in Manduca sexta larval development (early and late) impacted adult performance and fitness traits and whether thermal exposure of parents elicited plastic changes in offspring traits.
Meggan A. Alston +2 more
wiley +1 more source
Evaluation of the susceptibility of the pea aphid, Acyrthosiphon pisum, to a selection of novel biorational insecticides using an artificial diet [PDF]
An improved technique was developed to assay the toxicity of insecticides against aphids using an artificial diet. The susceptibility of the pea aphid Acyrthosiphon pisum (Harris) (Hemiptera: Aphidoidea) was determined for a selection of novel ...
Sadeghi, Amin +2 more
core +3 more sources

