Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP. [PDF]
The ecdysone receptor (EcR) possesses the remarkable capacity to adapt structurally to different types of ligands. EcR binds ecdysteroids, including 20-hydroxyecdysone (20E), as well as nonsteroidal synthetic agonists such as insecticidal dibenzoylhydrazines (DBHs).
Browning C+6 more
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In Silico Identification of Chemicals Capable of Binding to the Ecdysone Receptor. [PDF]
Abstract The process of molting, known alternatively as ecdysis, is a feature integral in the life cycles of species across the arthropod phylum. Regulation occurs as a function of the interaction of ecdysteroid hormones with the arthropod nuclear ecdysone receptor—a process preceding the triggering of a series of downstream events ...
Mellor CL+4 more
europepmc +6 more sources
Ecdysone Receptor (EcR) and Ultraspiracle Protein (USP) Genes From Conopomorpha sinensis Bradley Eggs: Identification and Expression in Response to Insecticides. [PDF]
Yao Q, Xu S, Dong Y, Quan L, Chen B.
europepmc +3 more sources
Ecdysone receptor isoforms play distinct roles in larval-pupal-adult transition in Leptinotarsa decemlineata. [PDF]
Xu QY+6 more
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Background: Indian ethnomedicine acclaims Tinospora cordifolia as a bone strengthening agent and prescribes it for the treatment of bone fractures, gout and other inflammatory diseases of the bone.
Ganesan Abiramasundari+2 more
doaj +2 more sources
Molecular Chaperones Activate the Drosophila Ecdysone Receptor, an RXR Heterodimer [PDF]
The steroid hormone 20-hydroxyecdysone coordinates the stages of Drosophila development by activating a nuclear receptor heterodimer consisting of the ecdysone receptor, EcR, and the Drosophila RXR receptor, USP. We show that EcR/USP DNA binding activity requires activation by a chaperone heterocomplex like that required for activation of the ...
Michelle N Arbeitman, David S. Hogness
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An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness. [PDF]
Lee S, Won M, Hwang RH, Hur GM, Ro H.
europepmc +3 more sources
Juvenile Hormone and Ecdysteroids Facilitate the Adult Reproduction Through the <i>Methoprene-Tolerant</i> Gene and <i>Ecdysone Receptor</i> Gene in the Female <i>Spodoptera frugiperda</i>. [PDF]
Zhang Y+7 more
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Molecular Characterization and Expression of the Ecdysone Receptor and Ultraspiracle Genes in the Wheat Blossom Midge, <i>Sitodiplosis mosellana</i>. [PDF]
Huang Q+4 more
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Insecticide selectivity: structure of a hemipteran ecdysone receptor LBD [PDF]
Michael C. Lawrence+7 more
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