Results 11 to 20 of about 7,003 (235)

Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP. [PDF]

open access: yesJ Pestic Sci, 2021
The ecdysone receptor (EcR) possesses the remarkable capacity to adapt structurally to different types of ligands. EcR binds ecdysteroids, including 20-hydroxyecdysone (20E), as well as nonsteroidal synthetic agonists such as insecticidal dibenzoylhydrazines (DBHs).
Browning C   +6 more
europepmc   +5 more sources

In Silico Identification of Chemicals Capable of Binding to the Ecdysone Receptor. [PDF]

open access: yesEnviron Toxicol Chem, 2020
Abstract The process of molting, known alternatively as ecdysis, is a feature integral in the life cycles of species across the arthropod phylum. Regulation occurs as a function of the interaction of ecdysteroid hormones with the arthropod nuclear ecdysone receptor—a process preceding the triggering of a series of downstream events ...
Mellor CL   +4 more
europepmc   +6 more sources

Selective Estrogen Receptor Modulator and prostimulatory effects of phytoestrogen β-ecdysone in Tinospora cordifolia on osteoblast cells

open access: goldJournal of Ayurveda and Integrative Medicine, 2018
Background: Indian ethnomedicine acclaims Tinospora cordifolia as a bone strengthening agent and prescribes it for the treatment of bone fractures, gout and other inflammatory diseases of the bone.
Ganesan Abiramasundari   +2 more
doaj   +2 more sources

Molecular Chaperones Activate the Drosophila Ecdysone Receptor, an RXR Heterodimer [PDF]

open access: bronzeCell, 2000
The steroid hormone 20-hydroxyecdysone coordinates the stages of Drosophila development by activating a nuclear receptor heterodimer consisting of the ecdysone receptor, EcR, and the Drosophila RXR receptor, USP. We show that EcR/USP DNA binding activity requires activation by a chaperone heterocomplex like that required for activation of the ...
Michelle N Arbeitman, David S. Hogness
openalex   +5 more sources

Insecticide selectivity: structure of a hemipteran ecdysone receptor LBD [PDF]

open access: hybridActa Crystallographica Section A Foundations of Crystallography, 2005
Michael C. Lawrence   +7 more
openalex   +2 more sources

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