Long-range repression by ecdysone receptor on complex enhancers of the insulin receptor gene [PDF]
Fly, 2023 The insulin signalling pathway is evolutionarily conserved throughout metazoans, playing key roles in development, growth, and metabolism. Misregulation of this pathway is associated with a multitude of disease states including diabetes, cancer, and ...
Katie D. Thompson +3 more
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Juvenile Hormone and Ecdysteroids Facilitate the Adult Reproduction Through the <i>Methoprene-Tolerant</i> Gene and <i>Ecdysone Receptor</i> Gene in the Female <i>Spodoptera frugiperda</i>. [PDF]
Int J Mol SciInsects, as the most diverse and numerous group in the animal kingdom, are at least partly dependent on the reproduction process, which is strictly regulated by the ‘classic’ insect hormones: juvenile hormone (JH), and 20-hydroxyecdysone (20E).
Zhang Y +7 more
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The 20-hydroxyecdysone agonist, halofenozide, promotes anti-Plasmodium immunity in Anopheles gambiae via the ecdysone receptor. [PDF]
Sci Rep, 2020 Mosquito physiology and immunity are integral determinants of malaria vector competence. This includes the principal role of hormonal signaling in Anopheles gambiae initiated shortly after blood-feeding, which stimulates immune induction and promotes ...
Reynolds RA +5 more
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In Silico Identification of Chemicals Capable of Binding to the Ecdysone Receptor. [PDF]
Environ Toxicol Chem, 2020 The process of molting, known alternatively as ecdysis, is a feature integral in the life cycles of species across the arthropod phylum. Regulation occurs as a function of the interaction of ecdysteroid hormones with the arthropod nuclear ecdysone ...
Mellor CL +4 more
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Ecdysone Receptor (EcR) and Ultraspiracle Protein (USP) Genes From Conopomorpha sinensis Bradley Eggs: Identification and Expression in Response to Insecticides. [PDF]
Front Physiol, 2020 Conopomorpha sinensis Bradley (Lepidoptera: Gracilariidae) is the dominant insect pest of litchi (chinensis Sonn.) and longan (Euphoria longan Lour.) fruit trees.
Yao Q, Xu S, Dong Y, Quan L, Chen B.
europepmc +2 more sources
The Drosophila ecdysone receptor promotes or suppresses proliferation according to ligand level. [PDF]
Dev Cell, 2023 Perez-Mockus G +5 more
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The ecdysone receptor complex is essential for the reproductive success in the female desert locust, Schistocerca gregaria. [PDF]
Sci Rep, 2019 Ecdysteroid hormones influence the development and reproduction of arthropods by binding a heterodimeric complex of nuclear receptors, the ecdysone receptor (EcR) and the retinoid-X-receptor/ultraspiracle (RXR/USP). Here, we report on the in vivo role(s)
Lenaerts C +3 more
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Bicistronic Expression of Ecdysone-Inducible Receptors in Mammalian Cells [PDF]
BioTechniques, 2001 The recent emergence of inducible expression systems for mammalian cells has greatly facilitated the in vivo analysis of gene function. The ecdysone-inducible expression system is particularly attractive because of (i) extremely low basal expression and ...
Denise L. Wyborski +2 more
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European Journal of Cell Biology, 2022 Bulk production and release of glue containing secretory granules takes place in the larval salivary gland during Drosophila development in order to attach the metamorphosing animal to a dry surface. These granules undergo a maturation process to prepare
Anikó Nagy +7 more
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Functional male accessory glands and fertility in Drosophila require novel ecdysone receptor. [PDF]
PLoS Genetics, 2017 In many insects, the accessory gland, a secretory tissue of the male reproductive system, is essential for male fertility. Male accessory gland is the major source of proteinaceous secretions, collectively called as seminal proteins (or accessory gland ...
Vandana Sharma +8 more
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