Cloning and Expression of Ecdysone Receptor and Retinoid X Receptor from Procambarus clarkii: Induction by Eyestalk Ablation. [PDF]
Dai TH +4 more
europepmc +3 more sources
Expression Analysis of Hormone Receptor 38 (HR38) and Ecdysone-Induced Protein 75 (E75) Genes and Their Functional Implications in the Development of <i>Heortia vitessoides</i> Moore. [PDF]
Liu N, Wang H, Liang J, Zhong Z, Lin T.
europepmc +3 more sources
Plasticity of the Ecdysone Receptor DNA Binding Domain [PDF]
Ecdysteroids coordinate molting and metamorphosis in insects via a heterodimer of two nuclear receptors, the ecdysone receptor (EcR) and the ultraspiracle (Usp) protein. Here we show how the DNA-recognition alpha-helix and the T box region of the EcR DNA-binding domain (EcRDBD) contribute to the specific interaction with the natural response element ...
Marek Orłowski +10 more
openalex +3 more sources
An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness. [PDF]
Lee S, Won M, Hwang RH, Hur GM, Ro H.
europepmc +3 more sources
The nuclear receptors of Biomphalaria glabrata and Lottia gigantea: Implications for developing new model organisms [PDF]
© 2015 Kaur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Antebi +131 more
core +10 more sources
Improved ecdysone receptor‐based inducible gene regulation system [PDF]
To develop an ecdysone receptor (EcR)‐based inducible gene regulation system, several constructs were prepared by fusing DEF domains of Choristoneura fumiferana EcR (CfEcR), C. fumiferana ultraspiracle (CfUSP), Mus musculus retinoid X receptor (MmRXR) to either GAL4 DNA binding domain (DBD) or VP16 activation domain.
Subba R, Palli +3 more
openaire +4 more sources
Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. [PDF]
BACKGROUND:A homologue of the ecdysone receptor has previously been identified in human filarial parasites. As the ecdysone receptor is not found in vertebrates, it and the regulatory pathways it controls represent attractive potential chemotherapeutic ...
Amruta S Mhashilkar +8 more
doaj +1 more source
Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. [PDF]
In insects, juvenile hormone (JH) and 20-hydroxyecdysone (20E) regulate larval growth and molting. However, little is known about how this cooperative control is terminating larval diapause especially in the bamboo borer, Omphisa fuscidentalis.
Suphawan Suang +7 more
doaj +1 more source
The ecdysone receptor promotes or suppresses proliferation according to ligand level
Steroid hormones control various cellular activities in a context-dependent manner. For example, ecdysone, which acts through a type II nuclear receptor, has seemingly opposite effects in Drosophila wing precursors, promoting proliferation during larval ...
Gantas Perez-Mockus +5 more
semanticscholar +1 more source
Molecular evidence for a functional ecdysone signaling system in Brugia malayi. [PDF]
BACKGROUND:Filarial nematodes, including Brugia malayi, the causative agent of lymphatic filariasis, undergo molting in both arthropod and mammalian hosts to complete their life cycles.
George Tzertzinis +7 more
doaj +1 more source

