Results 31 to 40 of about 7,003 (235)
Ecdysone acts through cortex glia to regulate sleep in Drosophila
eLife, 2023 Steroid hormones are attractive candidates for transmitting long-range signals to affect behavior. These lipid-soluble molecules derived from dietary cholesterol easily penetrate the brain and act through nuclear hormone receptors (NHRs) that function as
Yongjun Li +4 more
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Disease Models & Mechanisms, 2020 Aldosterone is produced by the mammalian adrenal cortex to modulate blood pressure and fluid balance; however, excessive, prolonged aldosterone promotes fibrosis and kidney failure.
Wenjing Zheng, Karen Ocorr, Marc Tatar
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Structure of the heterodimeric ecdysone receptor DNA-binding complex [PDF]
The EMBO Journal, 2003 Ecdysteroids initiate molting and metamorphosis in insects via a heterodimeric receptor consisting of the ecdysone receptor (EcR) and ultraspiracle (USP). The EcR-USP heterodimer preferentially mediates transcription through highly degenerate pseudo-palindromic response elements, resembling inverted repeats of 5'-AGGTCA-3' separated by 1 bp (IR-1). The
Andrzej Ożyhar +4 more
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Pigment dispersing factor regulates ecdysone biosynthesis via bombyx neuropeptide G protein coupled receptor-B2 in the prothoracic glands of Bombyx mori. [PDF]
PLoS ONE, 2014 Ecdysone is the key hormone regulating insect growth and development. Ecdysone synthesis occurs in the prothoracic glands (PGs) and is regulated by several neuropeptides.
Masatoshi Iga +3 more
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Revising Berg-Purcell for finite receptor kinetics [PDF]
, 2021 From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv +1 more source
Effects of methoxyfenozide on ecdysone receptor complex expression in larval Asian gypsy moth
Open Life Sciences, 2015 As a target of insect growth regulators, the ecdysone receptor complex binds ecdysone agonists to regulate gene transcription, development, and growth.
Wu Shao-ping +6 more
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PLoS ONE, 2023 Ecdysteroids control ovary growth and egg production through a complex gene hierarchy. In the female Rhodnius prolixus, a blood-gorging triatomine and the vector of Chagas disease, we have identified the ecdysone response genes in the ovary using ...
Samiha Benrabaa +2 more
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Ash2 acts as an ecdysone receptor coactivator by stabilizing the histone methyltransferase Trr
Molecular Biology of the Cell, 2012 The molting hormone ecdysone triggers chromatin changes via histone modifications that are important for gene regulation. On hormone activation, the ecdysone receptor (EcR) binds to the SET domain–containing histone H3 methyltransferase trithorax-related protein (Trr).
Albert Carbonell +3 more
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Steroid receptor coactivator TAIMAN is a new modulator of insect circadian clock.
PLoS Genetics, 2023 TAIMAN (TAI), the only insect ortholog of mammalian Steroid Receptor Coactivators (SRCs), is a critical modulator of ecdysone and juvenile hormone (JH) signaling pathways, which govern insect development and reproduction.
Vlastimil Smykal +10 more
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Steroid hormone ecdysone deficiency stimulates preparation for photoperiodic reproductive diapause.
PLoS Genetics, 2021 Diapause, a programmed developmental arrest primarily induced by seasonal environmental changes, is very common in the animal kingdom, and found in vertebrates and invertebrates alike.
Shuang Guo +6 more
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