Results 41 to 50 of about 3,650 (207)

Exposure to Structurally Related Organophosphate Esters Elicits Distinct Metabolomic Perturbations in Daphnia magna

Environmental Toxicology, EarlyView.
ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir, Sanam Yousifie, Karl J. Jobst, André J. Simpson, Myrna J. Simpson   +4 more
wiley   +1 more source

Ecdysteroids from the Stem Bark of Vitex doniana Sweet (Lamiaceae; ex. Verbenaceae): A Geographically Variable African Medicinal Species

, 2021
Vitex doniana Sweet is an African medicinal species that is prescribed as an aqueous bark extract to be applied topically or orally to achieve anti-infective outcomes. In select regions it is also taken orally as an antimalarial agent.
Jacinta R. Macdonald, Sani M. Isyaka, Fernandez-Cusimamani, Eloy, Musa I. Bunu, Macdonald, JR, Bunu, MI, Ndinteh, DT, Macdonald, Jacinta R., Isyaka, SM, Fernandez-Cusimamani, E, Nicholas J. Sadgrove, Langat, MK, Melnikovova, I, Ingrid Melnikovova, Sadgrove, Nicholas J., Isyaka, Sani M., Derek T. Ndinteh, Ndinteh, Derek T., Melnikovova, Ingrid, Moses K. Langat, Langat, Moses K., Eloy Fernandez-Cusimamani, Bunu, Musa I., Sadgrove, NJ   +23 more
core   +1 more source

Phytohormones and Elicitors Enhanced the Ecdysteroid and Glycosylflavone Content and Antioxidant Activity of Silene repens

Applied Sciences, 2021
In the course of the ongoing chemical study of species of Silene genus, S. repens Patrin as a common species of the genus, was selected as the object of this study.
Nina I. Kashchenko, Daniil N. Olennikov, Nadezhda K. Chirikova   +2 more
doaj   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source

Synthesis and Structure-Activity Relationships of Novel Ecdysteroid Dioxolanes as MDR Modulators in Cancer

Molecules, 2013
Ecdysteroids, molting hormones of insects, can exert several mild, non-hormonal bioactivities in mammals, including humans. In a previous study, we have found a significant effect of certain derivatives on the ABCB1 transporter mediated multi-drug ...
Ana Martins, József Csábi, Attila Balázs, Diána Kitka, Leonard Amaral, József Molnár, András Simon, Gábor Tóth, Attila Hunyadi   +8 more
doaj   +1 more source

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

Insect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li, Jie Chen, Zi‐Ye Wang, Fei‐Feng Wang, Lu‐Lu Dong, Jun Pan, Min‐Er Li, Lin Yu, Wen Sang   +8 more
wiley   +1 more source

It's Complicated: How Sex, Family, and Season Affect Growth of a Sexually Size Dimorphic Spider

Integrative Zoology, EarlyView.
Extreme female‐biased sexual size dimorphism (SSD) in Nephilingis cruentata emerges when male and female growth trajectories diverge mid‐development. Seasonal effects influence both sexes similarly, but family effects are strongly sex‐specific. These patterns identify a critical developmental window for mechanistic studies of SSD.
Tim Prezelj, Paul Vincent Debes, Rok Golobinek, Simona Kralj‐Fišer   +3 more
wiley   +1 more source

Evaluation of hydrogen bonds of ecdysteroids in the ligand-receptor interactions using a protein modeling system [PDF]

, 2009
The insect molting hormone, 20-hydroxyecdysone (20E) and its analogs (ecdysteroids) specifically bind to the ecdysone receptor. Previously, we synthesized various ecdysteroids containing the side chain moiety of ponasterone A (PonA), and measured the ...
Miyagawa, Hisashi, Akamatsua, Miki, Harada, Toshiyuki, Nakagawa, Yoshiaki, Yoshiaki Nakagawa, Miki Akamatsu, Toshiyuki Harada, Hisashi Miyagawa   +7 more
core   +1 more source

Role of ecdysteroids in the dynamics of insect haemolymph sugar [PDF]

In Bombyx 5th instar larvae, haemolymph trehalose concentrations were maintained in a range of 8-14 mM during the feeding period and then decreased to approximately half the level concomitantly with the occurrence of a gut purge. The decrease occurred as
Sakurai, Sho, 80143874, 15223, 16800, Iwami, Masafumi, 16799, 40193768, Uejima, Masanori, Oda, Yasunori, 11543   +9 more
core   +2 more sources

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source