Results 21 to 30 of about 2,081 (190)

Correction to the “Posters” for “bridging continents to advance life science 49th FEBS congress, 5–9 July 2025, Istanbul, Türkiye” [PDF]

FEBS Open Bio
FEBS Open Bio, Volume 15, Issue 12, Page 2101-2101, December 2025.
wiley   +2 more sources

Immunomodulatory Mechanisms of Rehmanniae Radix Praeparata–Achyranthes Root–Chinese Angelica Root Combination in Nontraumatic Osteonecrosis of the Femoral Head: A Comprehensive Network Pharmacology and Molecular Docking Study Focusing on Immunological Pathways [PDF]

Mediators of Inflammation, Volume 2025, Issue 1, 2025.
Objective Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating condition characterised by immune dysregulation and sterile inflammation, which are increasingly acknowledged as central pathogenic mechanisms. This study aims to identify the core herbal combination for NONFH and systematically explore its immunomodulatory effects and ...
Xin Li, Liqi Ng, Caiying Liu, Leilei Qin, Pengcheng Xiao, Chaozong Liu, Yusong Liu, Qiuping Zhang, Wei Huang, Yu Zhou, Wencai Liu   +10 more
wiley   +2 more sources

Network pharmacology and in silico analysis reveal Kochiae Fructus as a potential therapeutic against atopic dermatitis through immunomodulatory pathway interactions. [PDF]

PLoS ONE
Atopic dermatitis (AD), a chronic inflammatory disorder, poses significant therapeutic challenges owing to its complex pathophysiology, involving disrupted epidermal barrier function and immune dysregulation.
Shakeel Ahmad Khan
doaj   +2 more sources

Metabolomic Differentiation of Malpighiaceae From Dry and Humid Tropics via UHPLC‐MS/MS and Chemometrics [PDF]

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Various factors can trigger water stress in plants, particularly in those growing in dry tropical regions. To survive under such conditions, plants produce metabolites with adaptive functions. However, metabolomic data on the leaves of Malpighiaceae species cultivated in both dry and humid tropical areas of Brazil remain scarce.
Jaqueline Munise Guimarães da Silva, Rafael Felipe de Almeida, Maria Luiza Zeraik   +2 more
wiley   +2 more sources

Comparative metabolic profiling and quantitative analysis of metabolites in different tissues of Ajuga turkestanica by ESI-UHPLC-QqTOF-MS and NMR [PDF]

Scientific Reports
Ajuga turkestanica preparations are used as anti-aging cosmeceuticals and for medicinal purposes. Herein we describe the characterization and quantification of its metabolites in different organs using UHPLC-MS and NMR spectroscopy.
Nilufar Z. Mamadalieva, Michal Šoral, Elana Kysil, Pauline Stark, Andrej Frolov, Ludger A. Wessjohann   +5 more
doaj   +2 more sources

The nuclear receptors of Biomphalaria glabrata and Lottia gigantea: Implications for developing new model organisms [PDF]

, 2015
© 2015 Kaur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Antebi, A Aranda, A Bateman, A Daniel, A De Groot, A Heyland, A Le Maire, AC Chung, AE Lockyer, AE Lockyer, AE Lockyer, AE Lockyer, AE Lockyer, AE Sluder, AK Allen, AM Puinean, Anne E. Lockyer, AP Scott, AP Scott, B Stone, C Shiff, C Thummel, C Tyler, Catherine S. Jones, CB Burge, CJ Carter, CK Glass, CL Hultin, CM Adema, CM Adema, D Bouton, D Jones, D Lima, D Stange, DH Huson, DL Whitehead, E Enmark, Edwin J. Routledge, ER Levin, ES Ford, F Abascal, F Bonneton, F Ronquist, FM Sladek, G Benoit, G Escobedo, G Mitta, GN Eick, GV Markov, GV Markov, H Ueda, H Urushitani, H Zhang, H-R Koehler, I Letunic, J Auwerx, J Gutierrez-Mazariegos, J Keay, J Keay, J Oehlmann, J-M Wurtz, JT Bridgham, JT Bridgham, JW Thornton, K King-Jones, K King-Jones, K Tamura, L Chitsulo, L de F Tallarico, L-M Chen, LA Hertel, Leslie R. Noble, LFC Castro, LFC Castro, LN Rapado, M Garcia, M Kajiwara, M Knight, M Laguerre, M Pawlak, M Robinson-Rechavi, M Robinson-Rechavi, M Robinson-Rechavi, M Tillmann, M-JWA Schiffelers, MD Adams, ME Baker, ME Baker, MI Snow, N Raghavan, NE-SE-S Omran, O Simakov, P Matthiessen, P Matthiessen, P Thomas, PC Hanington, PC Hanington, PD Thomas, Peter P. Fong, PL Bardet, R Bannister, R Bannister, R Lafont, RA Velarde, RJ Greenspan, RM Sternberg, RM Sternberg, RT Yu, S Bertrand, S Kliewer, S Kumkate, S Pascoal, S Vogeler, SA Thomson, Satwant Kaur, SF Altschul, SH Golden, Susan Jobling, T Li, T Matsumoto, T Simoncini, TH Lindblom, TT Schug, W Wu, W Wu, W Wu, W Wu, X Ding, X Mu, Y Katsu, YG Jiang, ZD Zhang   +131 more
core   +15 more sources

Phytochemical characteristic and activity of medicinal raw material from the leaves of pharmacopoeial plant Rhaponticum carthamoides (Willd.) Iljin

Аграрная наука Евро-Северо-Востока, 2022
In 2016-2020 there was carried out a comprehensive study of the problem on involvement into the industrial turnover of ecdysterone-containing substance from the leaf parts of Rhaponticum carthamoides, which is included in the list of plants of the State ...
N. P. Timofeev
doaj   +1 more source

20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases

Biomedicines, 2021
There is growing interest in the pharmaceutical and medical applications of 20-hydroxyecdysone (20E), a polyhydroxylated steroid which naturally occurs in low but very significant amounts in invertebrates, where it has hormonal roles, and in certain ...
Laurence Dinan, Waly Dioh, Stanislas Veillet, Rene Lafont   +3 more
doaj   +1 more source

Quantitation of Ecdysterone and Targeted Analysis of WADA-Prohibited Anabolic Androgen Steroids, Hormones, and Metabolic Modulators in Ecdysterone-Containing Dietary Supplements

Separations, 2023
The aim of our research was to perform a comprehensive study of ecdysterone (ECD)-containing dietary supplements (DSs). Two analytical methods were optimised according to the expected concentration of the target compounds: quantitation of ECD by liquid ...
Zoltán Pálinkás, Dániel Békési, Margita Utczás   +2 more
doaj   +1 more source

An Arthropod Hormone, Ecdysterone, Inhibits the Growth of Breast Cancer Cells via Different Mechanisms

Frontiers in Pharmacology, 2020
Ecdysterone (Ecdy) is a hormone found in arthropods, which regulates their development. It is also synthesized by a number of plants to combat insect pests. It provides a number of beneficial pharmacological effects including the anabolic and adaptogenic
O. Shuvalov, O. Fedorova, E. Tananykina, Y. Gnennaya, A. Daks, A. Petukhov, A. Petukhov, N. A. Barlev, N. A. Barlev, N. A. Barlev   +9 more
doaj   +1 more source