Results 161 to 170 of about 2,198,221 (190)

Echinocandin Resistance in Candida Species Isolates from Liver Transplant Recipients.

open access: yesAntimicrobial Agents and Chemotherapy, 2017
International audienceABSTRACT Liver transplant recipients are at risk of invasive fungal infections, especially candidiasis. Echinocandin is recommended as prophylactic treatment but is increasingly associated with resistance.
Eric Dannaoui   +2 more
exaly   +2 more sources

Resistance to echinocandin-class antifungal drugs [PDF]

open access: yesDrug Resistance Updates, 2007
Invasive fungal infections cause morbidity and mortality in severely ill patients, and limited drug classes restrict treatment choices. The echinocandin drugs are the first new class of antifungal compounds that target the fungal cell wall by blocking beta-1,3-d-glucan synthase.
David S Perlin
exaly   +3 more sources

Candidemia surveillance in Iowa: emergence of echinocandin resistance

Diagnostic Microbiology and Infectious Disease, 2014
We performed prospective surveillance for candidemia at 14 Iowa hospitals in 2011-2012. A total of 163 episodes were analyzed. Candida albicans (n = 69 [42%]) and Candida glabrata (n = 58 [36%]) were the most common species. Antifungal resistance was uncommon; 9% of C.
Eiyu Matsumoto   +2 more
exaly   +3 more sources

Echinocandin Resistance in Candida Species: a Review of Recent Developments

Current Infectious Disease Reports, 2016
The echinocandins are important agents for the treatment of invasive fungal infections, especially those caused by Candida species. However, as with other antimicrobial agents, microbiologic resistance to this class of antifungal agents has emerged and can result in clinical failure.
Nathan Paul Wiederhold
exaly   +3 more sources

Molecular Detection of Resistance to Echinocandins

2016
In the last years, life-threatening fungal diseases have increased significantly, due to the rising number of human individuals susceptible to fungal infections, which are in part complicated by the emergence of antifungal drug-resistant pathogens.
Posteraro, Brunella   +3 more
openaire   +2 more sources

Discontinuation of echinocandin and azole treatments led to the disappearance of an FKS alteration but not azole resistance during clonal Candida glabrata persistent candidaemia

open access: yesClinical Microbiology and Infection, 2016
International audienceTo give an indication of a fitness cost conferred by FKS mutation–associated echinocandin resistance in Candida glabrata during human infection. Six C. glabrata clinical strains sequentially isolated from blood and a hepatic abscess
Hennequin Christophe   +2 more
exaly   +2 more sources

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