Results 31 to 40 of about 432 (139)

Vesicles from different Trypanosoma cruzi strains trigger differential innate and chronic immune responses

open access: yesJournal of Extracellular Vesicles, Volume 4, Issue 1, January 2015., 2015
Trypomastigote forms of Trypanosoma cruzi, the causative agent of Chagas Disease, shed extracellular vesicles (EVs) enriched with glycoproteins of the gp85/trans‐sialidase (TS) superfamily and other α‐galactosyl (α‐Gal)‐containing glycoconjugates, such as mucins. Here, purified vesicles from T.
Paula M. Nogueira   +11 more
wiley   +1 more source

The synthetic peroxide OZ78 is effective against Echinostoma caproni and Fasciola hepatica [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2006
The trematocidal properties of a synthetic peroxide, 1,2,4-trioxolane (OZ78) were determined both in vivo and in vitro.Two weeks post-infection Echinostoma caproni-infected mice were administered single oral doses of 400-1000 mg/kg OZ78. Fasciola hepatica-infected rats were treated orally with 50-400 mg/kg OZ78 3 and 8-9 weeks post-infection.
Keiser J   +4 more
openaire   +3 more sources

Characterization of the Complete Nuclear Ribosomal DNA Sequences of Paramphistomum cervi

open access: yesThe Scientific World Journal, Volume 2014, Issue 1, 2014., 2014
Sequences of the complete nuclear ribosomal DNA (rDNA) gene from five individual Paramphistomum cervi were determined for the first time. The five complete rDNA sequences, which included the 18S rDNA, the internal transcribed spacer 1 (ITS1), the 5.8S rDNA, the internal transcribed spacer 2 (ITS2), the 28S rDNA, and the intergenic spacer (IGS) regions,
Xu Zheng   +9 more
wiley   +1 more source

Pre‐ and postinfection priority effects have contrasting outcomes for parasite prevalence in host populations

open access: yesEcosphere, Volume 16, Issue 2, February 2025.
Abstract Parasite species frequently co‐occur more or less than expected by chance. These nonrandom co‐occurrence patterns can be driven by pre‐ or postinfection priority effects: parasites are more or less likely to attempt infection in a host already infected by another parasite species or may have higher or lower establishment and survival in hosts ...
Joshua I. Brian
wiley   +1 more source

Helminth Parasites Alter Protection against Plasmodium Infection

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
More than one‐third of the world’s population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease.
Víctor H. Salazar-Castañon   +3 more
wiley   +1 more source

Harnessing the Helminth Secretome for Therapeutic Immunomodulators

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
Helminths are the largest and most complex pathogens to invade and live within the human body. Since they are not able to outpace the immune system by rapid antigen variation or faster cell division or retreat into protective niches not accessible to immune effector mechanisms, their long‐term survival depends on influencing and regulating the immune ...
Dana Ditgen   +6 more
wiley   +1 more source

Unveiling the promise: Exosomes as game‐changers in anti‐infective therapy

open access: yesExploration, Volume 4, Issue 5, October 2024.
A comprehensive review to reveal new insights into exosomes’ distinctiveness, the growing availability of new analytical tools that drive the development of next‐generation synthetic systems were presented. Herein, light is shed on exosomes as drug delivery vehicles in anti‐infective therapy.
Vivek P. Chavda   +9 more
wiley   +1 more source

The endocytosis gene END3 is essential for the glucose‐induced rapid decline of small vesicles in the extracellular fraction in Saccharomyces cerevisiae

open access: yesJournal of Extracellular Vesicles, Volume 3, Issue 1, January 2014., 2014
Background Protein secretion is a fundamental process in all living cells. Gluconeogenic enzymes are secreted when Saccharomyces cerevisiae are grown in media containing low glucose. However, when cells are transferred to media containing high glucose, they are internalized.
Bennett J. Giardina   +2 more
wiley   +1 more source

Potential of extracellular vesicles in the pathogenesis, diagnosis and therapy for parasitic diseases

open access: yesJournal of Extracellular Vesicles, Volume 13, Issue 8, August 2024.
Abstract Parasitic diseases have a significant impact on human and animal health, representing a major hazard to the public and causing economic and health damage worldwide. Extracellular vesicles (EVs) have long been recognized as diagnostic and therapeutic tools but are now also known to be implicated in the natural history of parasitic diseases and ...
Ana Acacia Sá Pinheiro   +8 more
wiley   +1 more source

Cellular immune responses in Echinostoma caproni experimentally infected mice

open access: yesParasitology Research, 2011
The Echinostoma caproni-mice system is extensively used as an experimental model for the study of the factors involved in the establishment of chronic intestinal helminth infections. Although several parameters of the immunobiology of the host-parasite system have been studied in detail, the current knowledge of the cellular responses in these ...
Sotillo, Javier   +5 more
openaire   +4 more sources

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