Results 1 to 10 of about 11,628 (93)

Susceptibility and transcriptional characteristics of inbred C57BL/6J and outbred ICR mice in CDAHFD-induced MASH models [PDF]

open access: yesLaboratory Animal Research
Background Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive fibrotic liver disease, the underlying mechanisms of which have not been fully elucidated.
Jin Lu
exaly   +4 more sources

Comparison of Gut Microbiological Profiles of Inbred and Outbred Healthy Mice [PDF]

open access: yesMicrobiologyOpen
Gut microbes are closely related to host immunity and health, and mice are frequently used as a common model organism in biomedicine to study various diseases.
Dingyan Cao, Xudong Liu, Zilong He
exaly   +3 more sources

Shortcoming of the Mouse Model of Postoperative Ileus: Small Intestinal Lengths Have Similar Variations in In- and Outbred Mice and Cannot Be Predicted by Allometric Parameters [PDF]

open access: yesBiomedicines
Background/Objectives: The mouse model of postoperative ileus separates the gastrointestinal tract into 15 sections, 10 of which are in the small intestine, to measure intestinal transit time.
Maximiliane von Stumberg   +3 more
doaj   +2 more sources

Outbred ICR/CD1 mice display more severe neuroinflammation mediated by microglial TLR4/CD14 activation than inbred C57Bl/6 mice [PDF]

open access: yesNeuroscience, 2011
Neuroinflammation mediated by microglia is a pathological hallmark of many CNS disorders. Cell lines derived from inbred C57Bl/6 and outbred ICR/CD1 mice (BV-2 and N9 respectively), are often used to study microglial inflammatory activities. Although many studies demonstrate different responses of these cell lines to the same stimulus, no comparisons ...
M, Nikodemova, J J, Watters
exaly   +3 more sources

Outcome of Xenografted Fetal Porcine Pancreatic Tissue is Superior in Inbred Scid (C.B-17/Icr-scid/scid) Compared to Outbred Nude (CD-1-nu/nu) Mice

open access: yesCell Transplantation, 1999
Nude mice are used as recipients of foreign tissue because of their inability to reject these grafts. Our experience has been that there is variable rejection of fetal porcine insulin-producing tissue transplanted into CD-1 (athymic) outbred nude mice ...
Bernard E. Tuch Ph.D.   +1 more
doaj   +3 more sources

A Mouse Immunogenicity Model for the Evaluation of Meningococcal Conjugate Vaccines

open access: yesFrontiers in Immunology, 2022
The identification of an appropriate animal model for use in the development of meningococcal vaccines has been a challenge as humans are the only natural host for Neisseria meningitidis.
Arun B. Arunachalam   +2 more
doaj   +1 more source

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