Evaluation of a modified triple-combination anesthesia using dexmedetomidine in mice. [PDF]
Animal Model Exp MedDevelopment of a modified ketamine‐free anesthetic (dMMB) using dexmedetomidine. To improve the safety and recovery profile of conventional MMB, we developed dMMB by replacing medetomidine with dexmedetomidine. This ketamine‐free formulation showed comparable anesthetic depth and enhanced thermoregulation, avoiding unnecessary isomers for safer use ...
Watanabe M +5 more
europepmc +2 more sources
Hyperosmotic HEPES-CZB Enhances Post-ICSI Survival of C57BL/6N Mouse Oocytes. [PDF]
Reprod Med BiolABSTRACT Purpose This study aimed to determine whether performing intracytoplasmic sperm injection (ICSI) under transiently increased osmolality in HEPES‐CZB can improve post‐ICSI survival as well as embryo and offspring production in C57BL/6N mice. Methods HEPES‐CZB was supplemented with 0–200 mM NaCl or KCl, or 0–400 mM D(+)‐glucose or D(−)‐mannitol.
Yamaji K +4 more
europepmc +2 more sources
Journal of Animal Reproduction and Biotechnology, 2020 The establishment of porcine embryonic stem cells (ESCs) from porcine somatic cell nuclear transfer (SCNT) blastocysts is influenced by in vitro culture day of porcine reconstructed embryo and feeder cell type.
Na Rae Han +6 more
doaj +1 more source
Catheter colonization and abscess formation due to Staphylococcus epidermidis with normal and small-colony-variant phenotype is mouse strain dependent. [PDF]
PLoS ONE, 2012 Coagulase-negative staphylococci (CoNS) form a thick, multilayered biofilm on foreign bodies and are a major cause of nosocomial implant-associated infections.
Gunnar Sander +5 more
doaj +1 more source
Generation of live offspring from vitrified mouse oocytes of C57BL/6J strain. [PDF]
PLoS ONE, 2013 In mammals, unfertilized oocytes are one of the most available stages for cryopreservation because the cryopreserved oocytes can be used for assisted reproductive technologies, including in vitro fertilization (IVF) and intracytoplasmic sperm injection ...
Natsuki Kohaya +3 more
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Morphological association between the muscles and bones in the craniofacial region.
PLoS ONE, 2020 The strains of inbred laboratory mice are isogenic and homogeneous for over 98.6% of their genomes. However, geometric morphometric studies have demonstrated clear differences among the skull shapes of various mice strains.
Masahito Yamamoto +7 more
doaj +1 more source
Neural Regeneration Research, 2016 Induction of demyelination in the central nervous system (CNS) of experimental mice using cuprizone is widely used as an animal model for studying the pathogenesis and treatment of demyelination.
Kidsadagon Pringproa +4 more
doaj +1 more source
Complete genome sequences of new xenotropic murine leukemia viruses from the senescence-accelerated mouse (SAM): molecular and phylogenetic analyses. [PDF]
PLoS ONE, 2013 Approximately 10% of the mouse genome is constituted by endogenous retroviruses (ERVs), and a number of mouse ERVs remain active. Many copies of endogenous murine leukemia viruses (MuLVs) are detected in the genomes of inbred mouse strains. Some of these
Yun-Jung Lee +4 more
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Establishment of a mouse model of 70% lethal dose by total-body irradiation
Laboratory Animal Research, 2016 Whereas increasing concerns about radiation exposure to nuclear disasters or side effects of anticancer radiotherapy, relatively little research for radiation damages or remedy has been done. The purpose of this study was to establish level of LD70/30 (a
Seung-Hyun Ryu +11 more
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Comparison of commonly used ICR stocks and the characterization of Korl:ICR
Laboratory Animal Research, 2017 Mouse is a commonly used animal in life science studies and is classified as outbred if genetically diverse and inbred if genetically homogeneous. Outbred mouse stocks, are used in toxicology, oncology, infection and pharmacology research.
Hye-Jun Shin +7 more
doaj +1 more source