Results 31 to 40 of about 11,647 (107)

Effect of trehalose on the preservation of freeze-dried mice spermatozoa at room temperature

The Journal of Reproduction and Development, 2019
Freeze-drying of spermatozoa is a convenient and safe method to preserve mammalian genetic material without the use of liquid nitrogen or a deep freezer. However, freeze-dried spermatozoa (FD sperm) are not frequently used because of the low success rate
Daiyu ITO, Sayaka WAKAYAMA, Yuko KAMADA, Ikue SHIBASAKI, Satoshi KAMIMURA, Masatoshi OOGA, Teruhiko WAKAYAMA   +6 more
doaj   +1 more source

Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2

Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Ana Martín‐Sánchez, Daniela Jiménez‐Díaz, Rafael Esteve‐Pérez, Alexandru Vasile‐Tudorache, Jordan E. Read, Sasha R. Howard, Carmen Agustín‐Pavón   +6 more
wiley   +1 more source

Physiological properties of astroglial cell lines derived from mice with high (SAMP8) and low (SAMR1, ICR) levels of endogenous retrovirus

Retrovirology, 2008
Previous studies have reported that various inbred SAM mouse strains differ markedly with regard to a variety of parameters, such as capacity for learning and memory, life spans and brain histopathology.
Choi Eun-Kyoung, Jeong Byung-Hoon, Kim Jae-Il, Shin Hae-Young, Meeker Harry C, Kim Boe-Hyun, Carp Richard I, Kim Yong-Sun   +7 more
doaj   +1 more source

Importance of the interferon-α system in murine large intestine indicated by microarray analysis of commensal bacteria-induced immunological changes

BMC Genomics, 2008
Background Although microbiota play a critical role in the normal development and function of host immune systems, the underlying mechanisms, especially those involved in the large intestine (LI), remain unknown.
Takashima Kiyoe, Iizuka Seiichi, Imamura Sachiko, Nishiyama Mitsue, Anjiki Naoko, Yamamoto Masahiro, Munakata Kaori, Ishige Atsushi, Hioki Kyoji, Ohnishi Yasuyuki, Watanabe Kenji   +10 more
doaj   +1 more source

Genomic mapping of social behavior traits in a F2 cross derived from mice selectively bred for high aggression

BMC Genetics, 2010
Background Rapid response to selection was previously observed in mice selected for high levels of inter-male aggression based on number of attacks displayed in a novel social interaction test after isolation housing.
Perkins James, Buus Ryan J, Wang Shiliang, Nehrenberg Derrick L, de Villena Fernando, Pomp Daniel   +5 more
doaj   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, Volume 7, Issue 2, Page 266-270, May 2026.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

Guideline for the In Vivo Immunomodulatory Activity Test of Polysaccharide Based on Cyclophosphamide‐Induced Mouse Model

Food Safety and Health, Volume 4, Issue 2, Page 527-537, April 2026.
Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie, Xuecong Tong, Qiao Ding, Xiaojun Huang   +3 more
wiley   +1 more source

Establishment of a BALB/c Mouse Model for Photoaged Skin: Insights into UV‐Induced Dermatological Changes

Skin Research and Technology, Volume 32, Issue 4, April 2026.
ABSTRACT Background Photoaging, primarily induced by prolonged ultraviolet (UV) radiation exposure, significantly alters skin structure and function, necessitating models for deeper understanding and intervention development. This study aims to establish a BALB/c mouse model for investigating photoaging, leveraging their haired skin and genetic ...
Cuc Bach Huynh, Ngoc Bich Vu, Trung The Van, Phuc Van Pham   +3 more
wiley   +1 more source

Uncovering Hidden Phenotypes in NEX‐Cre Mice: Behavioral and Cellular Alterations Demand Re‐Evaluation of a Widely Used Transgenic Line

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Cre‐driver mouse lines are widely used for targeted gene manipulation, yet their baseline phenotypes are often assumed to be neutral. Here, we reveal hidden behavioral and synaptic alterations in the commonly used NEX‐Cre line, including changes in locomotion, anxiety‐like behavior, reward‐related behavior, and region‐specific dendritic spine density ...
Kim Renken, Olivia Andrea Masseck
wiley   +1 more source

Feeding Behaviour in the KPC Model of Pancreatic Cancer‐Associated Cachexia: Alteration of Spontaneous and Evoked Feeding Behaviours

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background The KPC mouse model of pancreatic cancer is gaining use in research, but detailed understanding of ingestive behaviour changes in this and other cachexia models is limited. Methods Male C57BL/6 J mice (7 weeks) were maintained under standard feed (PicoLab5L0D) and housing conditions (12:12 h; Light:Dark).
Fateema Muzaffar, William F. Colmers, Vickie E. Baracos   +2 more
wiley   +1 more source