Results 11 to 20 of about 13,488 (203)
Cytolytic replication of echoviruses in colon cancer cell lines [PDF]
Virology Journal, 2011 Background Colorectal cancer is one of the most common cancers in the world, killing nearly 50% of patients afflicted. Though progress is being made within surgery and other complementary treatments, there is still need for new and more effective ...
Gullberg Maria +3 more
doaj +3 more sources
Frontiers in Medicine, 2023 Echovirus 18 has been recognized as an important causative pathogen of aseptic meningitis in young children worldwide, and echovirus 18-induced meningitis is rarely found in adults with immunocompetence.
Chunmei Jiang +14 more
doaj +1 more source
Viruses, 2022 Our work focused on comparing the cellular effects of Rigvir to other echovirus 7 isolates, because originally Rigvir is also an echovirus 7 isolate [...]
Eero Hietanen, Petri Susi
doaj +1 more source
Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18
mBio, 2022 Virus-receptor interactions determine viral host range and tissue tropism. CD55 and human neonatal Fc receptor (FcRn) were found to be the binding and uncoating receptors for some of the echovirus-related enterovirus species B serotypes in our previous ...
Xiangpeng Chen +14 more
doaj +1 more source
Investigation and successful control of an echovirus 11 outbreak in neonatal intensive care units
Pediatrics and Neonatology, 2020 Background: Echovirus 11 emerged as a predominant enterovirus strain and was associated with neonatal mortalities in Taiwan in 2018. We investigated an echovirus 11 outbreak in the neonatal intensive care units (NICUs) in a tertiary hospital in northern ...
Sheng-Yuan Ho +9 more
doaj +1 more source
Novel Synergistic Anti-Enteroviral Drug Combinations
Viruses, 2022 Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: We have tested our library of
Aleksandr Ianevski +7 more
doaj +1 more source
Therapeutics for fulminant hepatitis caused by enteroviruses in neonates
Frontiers in Pharmacology, 2022 Neonatal infection with nonpolio enteroviruses (EVs) causes nonspecific febrile illnesses and even life-threatening multiorgan failure. Hepatitis, which often results in hepatic necrosis followed by disseminated intravascular coagulopathy, is one of the ...
Li-Chiu Wang +6 more
doaj +1 more source
The Turkish Journal of Pediatrics, 2020 Background. Mild encephalopathy with reversible splenial lesion (MERS), a clinic-radiological syndrome distinguished by reversible encephalopathy onset, has been increasingly recognized in Caucasian children. Case.
Enrico Masiello +5 more
doaj +1 more source
Hsp70 Is a Potential Therapeutic Target for Echovirus 9 Infection
Frontiers in Molecular Biosciences, 2020 Echovirus is an important cause of viral pneumonia and encephalitis in infants, neonates, and young children worldwide. However, the exact mechanism of its pathogenesis is still not well understood. Here, we established an echovirus type 9 infection mice
Yang Wang +8 more
doaj +1 more source
Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling. [PDF]
, 2017 Conformational activation of integrins is generally required for ligand binding and cellular signalling. However, we have previously reported that the nonactivated conformation of α2β1 integrin can also bind to large ligands, such as human echovirus 1 ...
Cheng, R Holland +5 more
core +2 more sources