Age-dependent discordance in chemiluminescent immunoassay-electrochemiluminescence immunoassay correlation for 25-hydroxyvitamin D measurement reveals methodological considerations for assessment in early infancy [PDF]
Vitamin D (VD) status is assessed by measuring serum 25-hydroxyvitamin D (25(OH)D) levels using immunoassays. In December 2024, a Japanese diagnostic laboratory transitioned from chemiluminescent immunoassay (CLIA: LIAISON® 25 OH Vitamin D Total Assay ...
Masashi Ota +5 more
doaj +2 more sources
Introduction: Anti-thyroid peroxidase autoantibodies (TPO) is an essential diagnostic tool for autoimmune disorders of the thyroid gland. However, TPO results are not always comparable due to differences between methods. Here, we aimed to investigate the
Manescu Ion Bogdan +4 more
doaj +2 more sources
Background: Cyclosporine (CsA) and tacrolimus (TAC) are immunosuppressant drugs that are often used to treat autoimmune diseases and as transplantation therapy; therefore, their concentrations need to be monitored carefully.
Maki Sasano +3 more
doaj +2 more sources
Objectives: Liquid chromatography tandem mass spectrometry (LC-MS/MS) is the gold standard for measurement of immunosuppressive drugs (ISDs), but is technically demanding and less accessible in resource-limited countries.
Amy Strydom +4 more
doaj +2 more sources
Interference of hemolysis on the postmortem biochemical analysis of IgE by ECLIA [PDF]
Forensic diagnosis of anaphylactic shock is a challenging task in forensic practice due to the lack of characteristic morphological changes. Postmortem analysis of serum IgE can provide helpful information for determining anaphylaxis. However, postmortem serum always suffers from hemolysis.
Tianqi Wang +4 more
openaire +2 more sources
An Enhanced Electrochemiluminescence Immunoassay Platform via Optimized Magnetic Bead Uniformity for Reliable Thyroid-Stimulating Hormone Monitoring [PDF]
Electrochemiluminescence immunoassay (ECLIA) is widely used in clinical diagnostics owing to its high sensitivity, broad dynamic range, and excellent analytical stability.
Hengbo Lei +4 more
doaj +2 more sources
Biotin interference in several electrochemiluminescence immunoassays (eclia) [PDF]
– Background: The aim of this study is to define the interference of biotin in several endocrine, tumor marker, and vitamin assays performed by an electrochemiluminescence method, trying to determinate the critical level that causes biotin interference. – Material and methods: Working biotin solutions were prepared in phosphate-buffered saline (PBS) at
openaire +1 more source
Clinical Evaluation of Serological Diagnostic Assays for COVID-19 Antibody Detection [PDF]
Objective: This study was aimed to evaluate the laboratory performance of three different serological assays(Immuno fluorescence Assay (IFA), Electrochemiluminescence Immunoassay (ECLIA) and Chemiluminescent Microparticle Immunoassay (CMIA) to see if ...
Hijab Batool, Muhammad Dilawar Khan, Omar Rasheed Chughtai, Akhtar Sohail Chughtai, Shakeel Asharf, Saqib Shahzad
doaj +1 more source
Evaluation of ECLIA antigen detection tests as screening methods for COVID-19 in comparison with molecular analysis [PDF]
Data from literature shows that antigen tests are rapid and helpful tools for diagnosis of COVID-19.This work aimed to evaluate the performances of the Elecsys SARS-CoV-2 Antigen test, in comparison to RT-qPCR, the gold standard.A total of 110 swabs were tested; according to rRT-PCR, 76 were positive, and 34 were negative.
Kolesova, O. +8 more
openaire +3 more sources
Correlation between anti-SARS-CoV-2 antibody titers in ELISA and COI in ECLIA.
The correlation between SARS-CoV-2 antibody titers in ELISA and cutoff indexes (COIs) in ECLIA in blood samples collected from 143 cruise ship crew members who had positive first SARS-CoV-2 genetic test results were evaluated using Spearman’s rank-order ...
Hiroo Hasegawa (3586247) +16 more
core +1 more source

