Results 231 to 240 of about 227,914 (337)

Generation of high-quality single-stranded DNA for full-length and truncated genome standards of recombinant adeno-associated viruses. [PDF]

Mol Ther Methods Clin Dev
Manz J, Ruppert R, Haindl M, Hubbuch J, Graf T, Pschirer J.   +5 more
europepmc   +1 more source

The Functional Epididymal Amyloid Cystatin‐Related Epididymal Spermatogenic (CRES) is a Component of the Mammalian Brain Extracellular Matrix

Journal of Neuroscience Research, Volume 104, Issue 1, January 2026.
This study investigated if the epididymal amyloid CRES (cystatin‐related epididymal spermatogenic) is present in the male and female mammalian brain. CRES is expressed by hippocampal astrocytes, CA2 and CA3 neurons, and exhibits amyloid properties in the extracellular matrix.
Alejandra Gomez, Uyen T. Tran, Petar N. Grozdanov, Gail A. Cornwall   +3 more
wiley   +1 more source

Genome-shock deletion of a hybrid lethality gene breaks a reproductive barrier and facilitates speciation in <i>Nicotiana</i>. [PDF]

Front Plant Sci
Nagai S, Kawaguchi K, Itakura H, Matsumoto K, Iizuka T, Kobayashi K, Nakata K, Yamada T, Marubashi W, Yanase M, Morikawa T, Yokoi S, Tezuka T.   +12 more
europepmc   +1 more source

Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK Pathways

MedComm, Volume 7, Issue 1, January 2026.
Ramalin alleviates Alzheimer's disease pathology by selectively inhibiting HDAC6, reducing BACE1 levels, and suppressing neuroinflammation through downregulation of the NLRP3 inflammasome and iNOS. It restores synaptic function impaired by Aβ toxicity and improves cognitive performance in AD mouse models, APP/PS1 and 3xTg‐AD.
Yongeun Cho, Jeongmi Lee, Bo Youn Choi, Jin‐Ho Yun, Sukmin Han, Seung Hyun Baek, Jinsu Park, Yoonsuk Cho, Hark Kyun Kim, Eunae Kim, Leon F. Palomera, Jeein Lim, Yeji Jeon, Jeonghyeong Im, Ju‐Mi Hong, Tai Kyoung Kim, Sung Hyun Kim, Joung Han Yim, Dong‐Gyu Jo   +18 more
wiley   +1 more source

Synthetic guide sequence to generate CRISPR-Cas9 entry strains in <i>C. elegans</i>. [PDF]

MicroPubl Biol
Lange KI.
europepmc   +1 more source

Dynamic interaction of the Yersinia pseudotuberculosis type three secretion system proteins LcrV and LcrG

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Yersinia pathogenicity is dependent on polarized translocation of effector proteins via the type III secretion system (T3SS). The tip complex situated on the needle structure of the T3SS is required for contact with the eukaryotic host membrane and is to an extent composed of pentameric LcrV. LcrV is a multifunctional protein that also acts as
Jagadish Chandra Kumar Mangu, Per Rogne, Jonna Mattsson, Lucas Hultgren, Kumar D. Gahlot, Anaïs Lamy, Ronnie P.‐A. Berntsson, Lennart B.‐Å. Johansson, Matthew S. Francis, Magnus Wolf‐Watz   +9 more
wiley   +1 more source

Site directed mutagenesis experiments suggest that Glu lll, Glu 144 and Arg 145 are essential for endonucleolytic activity of EcoRI

, 1986
Heiner Wolfes, Jürgen Alves, Anja Fließ, Robert Geiger, Alfred Pingoud   +4 more
openalex   +2 more sources

Detergents alter the stability and lipid binding properties of the CD1d immunoreceptor

Protein Science, Volume 35, Issue 1, January 2026.
Abstract CD1d, a non‐classical immunoreceptor, plays a central role in lipid antigen presentation to a variety of T cell types. Despite the widespread use of detergents to measure and manipulate lipid/CD1d interactions in vitro, in situ, and in vivo, the molecular basis by which detergents influence the stability of CD1d and its lipid binding ...
Uri Z. Miles, M. G. Finn, Andrew C. McShan   +2 more
wiley   +1 more source

Characterization of five environmental phages infecting <i>Escherichia coli</i> K-12 isolated during a phage biology training course. [PDF]

Microbiol Spectr
Shyrokova L, Egorov AA, Cole A, Duque-Pedraza JJ, Tyagi A, Ernits K, Mets T, Kurata T, Juozapaitis J, Yang ALJ, Ibarra Chavez R, Graversgaard Henriksen FO, Lassen S, Atkinson GC, Hauryliuk V, Johansson MJO.   +15 more
europepmc   +1 more source

Phage‐Mediated Presentation of a Conserved HA2 Epitope From Influenza A Virus Elicits Significant IgY Antibody Responses in Broiler Chickens

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
The conserved region of HA2 peptide of Influenza A virus was expressed on the surface of Protein VIII from M13 phage. Immunization of broiler chickens by this hybrid phage showed high levels of antibody responses, highlighting its potential as a promising tool for universal vaccine development against Influenza A virus.
Zinat Lotfi, Mehdi Golchin, Mohammad Ali Shamshirgaran   +2 more
wiley   +1 more source