Results 31 to 40 of about 35,578 (172)

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Outbreak of contagious ecthyma caused by Orf virus (Parapoxvirus ovis) in a vaccinated sheep flock in Uruguay.

, 2022
:Orf virus (ORFV) causes contagious ecthyma (CE), a highly transmissible, zoonotic disease of small ruminants. CE mostcommonly affects lambs and unvaccinated sheep.
FLORES, E.F., GIANNITTI, F., CARGNELUTTI ,J.F., RIET-CORREA, F., COSTA, R.A. DA, SCHILD, C.   +5 more
core   +1 more source

Knowledge, Attitudes and Practices Regarding Livestock Diseases Among Residents of East Gojjam Zone, Amhara Region, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This study reveals gaps in livestock owners’ knowledge and practices regarding disease prevention and control in East Gojjam Zone, Ethiopia, highlighting the need for strengthened veterinary extension services and community education to improve animal health management.
Liuel Yizengaw, Haregua Yesigat, Kifile Wondimagegnehu, Arega Tafere, Habtamu Yalew, Dessalew Habtie, Natenael Teshager, Yibeltal Simeneh   +7 more
wiley   +1 more source

Characterization of Normal and Ozone Stressed Moringa Mediated Silver (Ag) Nanoparticles (AgNPs) and Plant Crude Extract Against Pathogenic Strains

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
Graphical representation of characterization of Moringa mediated silver nanoparticles and crude plant extract under normal and ozone stress conditions against pathogenic strains. ABSTRACT Nanotechnology is the manipulation of matter at the atomic scale and has evolved as a promising discipline with many applications such as medicine, diagnosis, and ...
Misbah Zaid Ali, Zia Ullah, Sabaz Ali Khan, Rafiq Ahmad, Nadia Bibi, Hira Mushtaq, Bushra Rehman, Qamar Sajjad, Awais Raza, Agoura Diantom   +9 more
wiley   +1 more source

Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health

Journal of Applied Ecology, Volume 62, Issue 11, Page 2894-2913, November 2025.
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley   +1 more source

Granulomatous mural folliculitis and cytotoxic interface dermatitis in a pygmy goat associated with ovine herpesvirus‐2 and systemic lesions of malignant catarrhal fever

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract A 1‐year‐old pygmy goat presented with progressive alopecia, skin ulceration and lichenification over the neck, face and body. Empirical treatment for parasitic and fungal causes of skin disease did not produce clinical improvement, prompting a full diagnostic investigation.
Peter Richards‐Rios, Dominic Sharkey
wiley   +1 more source

Advancing ORFV‐Based Therapeutics to the Clinical Stage

Reviews in Medical Virology, Volume 35, Issue 3, May 2025.
ABSTRACT The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses without inducing significant anti‐vector immunity.
Matthias Helmold, Ralf Amann
wiley   +1 more source

Outbreak of contagious ecthyma in camels (Camelus dromedarius and Camelus bactrianus) in Southwest Iran

, 2014
Camel contagious ecthyma (CCE) is a highly infectious viral skin disease of sheep, goats, and camels caused by a Parapoxvirus. This study reports an outbreak of CCE in a herd of 34 camels/dromedaries, with 24 infected animals.
H. R. Varshovi, M. Goudarzi, M. Khalaj, E. Gharib Mombeni, M. Gharib Mombeini, M. Kenarkohi, S. M. Mousavi Nasab   +6 more
core   +1 more source

Hyalomma marginatum in Europe: The Past, Current Status, and Future Challenges—A Systematic Review

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Hyalomma marginatum is a prominent tick vector responsible for transmitting various pathogens, including the Crimean–Congo hemorrhagic fever virus (CCHFV), across Europe. This systematic review consolidates findings from 144 publications regarding the geographical distribution of H. marginatum and its associated pathogens.
Seyma S. Celina, Jiří Černý, Zongfu Wu   +2 more
wiley   +1 more source

The changes in the levels of elements in sheep with Contagious Ecthyma

, 2018
This study has aimed to investigate the differences between the levels of trace elements in sheep with the diagnosis of ecthyma, and in healthy sheep. For this purpose, Be,Bi,Pb,Cd,Na,K,Ca,Mg,Fe,Cu,Zn,Se,Ni and Mn,Co,Cr,Li elements in the plasma of sheep
Karapinar, Zeynep, Mis, Leyla, Asli Çilingir Yeltekin, Yeltekin, Aslı Çilingir, Leyla Mis, Zeynep Karapinar   +5 more
core   +1 more source