Results 41 to 50 of about 1,255 (201)

Construction and characterization of a contagious ecthyma virus double-gene deletion strain and evaluation of its potential as a live-attenuated vaccine in goat

open access: yesFrontiers in Immunology, 2022
Contagious ecthyma is a highly contagious viral disease with zoonotic significance caused by orf virus (ORFV) that affects domestic, ruminants and humans.
Zhen Zhu   +8 more
doaj   +1 more source

Detection and phylogenetic analysis of Orf virus from sheep in Brazil: a case report

open access: yesVirology Journal, 2009
Background Orf virus (ORFV), the prototype of the genus Parapoxvirus (PPV), is the etiological agent of contagious ecthyma, a severe exanthematic dermatitis that afflicts domestic and wild small ruminants.
Bonjardim Cláudio A   +8 more
doaj   +1 more source

Comparison of contagious ecthyma virus genomes by restriction endonucleases

open access: yes, 1985
Restriction enzyme analysis with KpnI revealed heterogeneity among 10 different strains of contagious ecthyma virus from sheep, muskox, Dall sheep and humans.
Rafii, F.   +3 more
core   +1 more source

Molecular Insights into the Genetic Variability of ORF Virus in a Mediterranean Region (Sardinia, Italy)

open access: yesLife, 2021
Orf virus (ORFV) represents the causative agent of contagious ecthyma, clinically characterized by mild papular and pustular to severe proliferative lesions, mainly occurring in sheep and goats.
Elisabetta Coradduzza   +12 more
doaj   +1 more source

Immunohistochemical Evaluation of TLR‐4, HSP‐70 and Caspase‐3 Expressions in Lesional Areas of Ecthyma Disease

open access: yesVeterinary Dermatology, EarlyView.
Background: Contagious ecthyma (Orf) is a highly contagious, economically significant disease affecting sheep, goats and wild small ruminants, caused by the resilient Orf virus (ORFV). It produces thick, crusted lesions around the mouth and nostrils, especially in animals aged 3–4 months, sometimes causing near 100% mortality in immunocompromised young
Emine Nur Dincer, Ozlem Ozmen
wiley   +1 more source

TaqMan-based real-time quantitative fluorescence PCR for detection of Orf virus

open access: yesIndian Journal of Animal Sciences, 2019
Contagious ecthyma, also known as scabby mouth or Orf, is a zoonosis, which is caused by the Orf virus (ORFV). Human contact with infected animals can cause cutaneous lesions.
YU-SHENG LIN, JIN-XIU JIANG
doaj   +1 more source

Molecular characterization and phylogenetic analysis of orf virus isolated from goats in Sokoto metropolis, Nigeria

open access: yesFuture Science OA, 2021
Aim: The aim of this study was to molecularly characterize orf virus isolated from clinical infections in goats in Sokoto metropolis. Materials & methods: Embryonated chicken eggs were used to isolate orf virus according to the established protocol ...
Nafi'u Lawal   +8 more
doaj   +1 more source

Pseudocowpox Virus:The Etiological Agent of Contagious Ecthyma (Auzdyk) in Camels (Camelus dromedarius)in the Arabian Peninsula

open access: yes, 2007
We have determined the nucleotide sequence of DNA extracted from pustules, saliva, and blood of camels presenting with contagious ecthyma, in Bahrain and also from a sample (SACamel) of infected tissue from a camel that had presented with contagious ...
Housawi, F. M. T.   +12 more
core   +1 more source

A Rare Case of Oral Papillomatosis in a Goat Kid

open access: yesCase Reports in Veterinary Medicine, 2022
The clinical management and outcome of a case of caprine papillomatosis in a 2-week-old kid goat was reported. Based on the PCR result, contagious ecthyma (CE) was ruled out.
Mohammed Naji Ahmed Odhah   +3 more
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

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