Trophectoderm-like cells from EPS cells enable generating EPS cell-derived post-implantation embryoids that complete gastrulation. [PDF]
Wang X +10 more
europepmc +1 more source
ABSTRACT Background and Aim As dental anomalies can significantly affect esthetic and function, early detection and diagnosis are crucial for treatment and minimizing potential negative effects. Artificial intelligence (AI) has emerged as a promising tool for the segmentation and detection of dental anomalies in number, morphology, size, position, and ...
Mobina Sadat Zarabadi +4 more
wiley +1 more source
Specialized signaling centers direct cell fate and spatial organization in a mesodermal organoid model. [PDF]
Skoufa E +15 more
europepmc +1 more source
Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho +2 more
wiley +1 more source
Establishment of a human inner ear model reveals that gentamicin C2b is substantially less ototoxic than clinical gentamicin. [PDF]
Jeong M +4 more
europepmc +1 more source
ABSTRACT Percutaneous osseointegrated (OI) devices offer an advanced alternative to socket prosthetic suspension systems for amputees but can face clinical limitations due to complications at the skin‐implant interface. Titanium (Ti) and its alloys, though mechanically suitable and promoting osseointegration, are unable to support epidermal cell ...
Samantha K. Steyl +7 more
wiley +1 more source
An Integrated Canonical and Non-Canonical Wnt Signaling Network Controls Early Anterior-Posterior Axis Formation in Sea Urchin Embryos. [PDF]
Fenner JL +4 more
europepmc +1 more source
A Clearer Picture: Using Fetal MRI to Diagnose Neck Masses and Predict Airway Compromise
ABSTRACT Introduction Fetal neck masses are rare but can be life‐threatening if causing airway compromise. Early and accurate diagnosis of these masses allows life‐saving interventions to be undertaken at birth in the form of the EXIT procedure. Methods A single institution case series of all patients referred for fetal MRI to a tertiary center in the ...
Louise Wilson +2 more
wiley +1 more source
Positional programs in early murine facial development and their role in human facial shape variability. [PDF]
Murillo-Rincón AP +6 more
europepmc +1 more source
Bilateral Eyelid Agenesis With Multiple Congenital Ocular Anomalies in an Australian Labradoodle Puppy: Case Report and Surgical Management [PDF]
ABSTRACT A 15‐week‐old Australian Labradoodle puppy was presented to The University of Queensland Small Animal Hospital for bilateral eyelid agenesis/coloboma and associated ocular complications. Enucleation of the left globe and repair of the right eyelid via a lip‐to‐lid transmucosal flap was performed. Given the subsequent development of prolapse of
Ng C +4 more
europepmc +2 more sources

