Results 191 to 200 of about 63,560 (282)

Meflin/ISLR is a meningeal cell‐specific marker involved in the development of meninges and meningioma progression

Brain Pathology, Volume 36, Issue 2, March 2026.
Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki, Tomotsugu Kurauchi, Akitoshi Hara, Nobutoshi Esaki, Shinji Mii, Ryota Ando, Akihiro Sakai, Kuniaki Tanahashi, Fumiharu Ohka, Ryuta Saito, Atsushi Natsume, Yuki Hattori, Takaki Miyata, Atsushi Enomoto   +13 more
wiley   +1 more source

Notch Signalling Plays a Role in Patterning the Ventral Mesoderm During Early Embryogenesis in <i>Drosophila melanogaster</i>. [PDF]

Int J Mol Sci
Megaly M, Foran G, Ali A, Turgambayeva A, Sengsouriya T, Berube S, Hallam RD, Liang P, Necakov A.   +8 more
europepmc   +1 more source

Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing

Cancer Science, Volume 117, Issue 3, Page 797-806, March 2026.
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima, Sho Kurihara, Isamu Saeki, Ryo Touge, Keigo Nakashima, Shuhei Karakawa, Fumiyuki Yamasaki, Satoshi Okada, Eiso Hiyama   +8 more
wiley   +1 more source

Segregation of endoderm and mesoderm germ layer identities in the diploblast Nematostella vectensis. [PDF]

Nat Commun
Haillot E, Lebedeva T, Steger J, Genikhovich G, Montenegro JD, Cole AG, Technau U.   +6 more
europepmc   +1 more source

Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis

Cell Proliferation, Volume 59, Issue 3, March 2026.
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang, Miao Yu, Hangbo Liu, Kai Sun, Chenxin Geng, Haochen Liu, Hailan Feng, Yang Liu, Hu Zhao, Dong Han   +9 more
wiley   +1 more source

DNA methylation as a biomarker of prenatal exposures: current challenges and opportunities. [PDF]

Environ Epigenet
Walkup RB, Nangle MA, Bergmann PE, Lipinski RJ.   +3 more
europepmc   +1 more source

Constructing the spatiotemporal atlas of single-cell lineage trajectories in stereotypic biological structures. [PDF]

iScience
Wang R, Yang X, Lian C, Wang J, Chen J, Qian Y, Xu Y, Wang L, Marioni JC, Tam PPL, Jing N.   +10 more
europepmc   +1 more source

A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders

Experimental Dermatology, Volume 35, Issue 3, March 2026.
ABSTRACT Ankyloblepharon‐ectodermal defects‐cleft lip/palate (AEC) is a disorder caused by autosomal‐dominant mutations in the TP63 gene. AEC is characterised by the presence of severe and painful skin erosions that can take years to heal. Current treatment options for these devastating lesions are limited, highlighting the need for new therapeutic ...
Maddison N. Salois, Saiphone Webb, Isaiah A. Proctor, Peter J. Koch, Maranke I. Koster   +4 more
wiley   +1 more source

A chemical epigenetic tool to probe site-specific DNA-binding protein complexes. [PDF]

Proc Natl Acad Sci U S A
Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Chen S, Schultz PG.   +10 more
europepmc   +1 more source

Congenital Ectodermal Dysplasia [PDF]

British Journal of Ophthalmology, 1955
openaire   +2 more sources