Results 11 to 20 of about 5,633 (211)

Ectoine degradation pathway in halotolerant methylotrophs.

PLoS ONE, 2020
BACKGROUND:Microorganisms living in saline environments are forced to regulate turgor via the synthesis of organic osmoprotective compounds. Microbial adaptation to fluctuations in external salinity includes degradation of compatible solutes.
Aleksander S Reshetnikov, Olga N Rozova, Yuri A Trotsenko, Sergey Yu But, Valentina N Khmelenina, Ildar I Mustakhimov   +5 more
doaj   +4 more sources

High production of ectoine from methane in genetically engineered Methylomicrobium alcaliphilum 20Z by preventing ectoine degradation

Microbial Cell Factories
Background Methane is a greenhouse gas with a significant potential to contribute to global warming. The biological conversion of methane to ectoine using methanotrophs represents an environmentally and economically beneficial technology, combining the ...
Sang Eun Lim, Sukhyeong Cho, Yejin Choi, Jeong-Geol Na, Jinwon Lee   +4 more
doaj   +3 more sources

An Efficient CO₂-Upcycling Platform Based on Engineered Halomonas TD with Enhanced Acetate-Utilizing Capacity via Adaptive Laboratory Evolution. [PDF]

Adv Sci (Weinh)
An electrochemical system is designed to convert CO2 into CO2‐derived electrolytes (CDE), mainly containing acetate and formate. The underlying mechanism of acetate metabolism in Halomonas TD80 is explored via ALE. Engineered TD80 produced high‐yield diversified products from CDE.
Wang C, Chen TT, Yang YJ, Li YX, Chang YX, Xiao YC, Guo WT, Zheng Y, Deng RZ, Tian YX, Situ W, Shen HW, Chen Y, Wang YB, Xing J, Wang H, Xia L, Lin YN, Ye JW.   +18 more
europepmc   +2 more sources

Pre-irradiation effects of ectoine on radiation-induced cardiotoxicity in female Swiss albino mice model

Archives of Pharmaceutical Sciences Ain Shams University, 2022
Background: Ectoine is a compatible solute that acts as a natural protectant. In mice model, a single post-irradiation ectoine dose showed protective effects by modulating both inflammatory and oxidative stress pathways.
Sameh Nakhla, Basma Albehery, Sana Shawky, Salwa Lotfi, Metwali Kotb, Emad El-Bassiouni, Eman El-Abd   +6 more
doaj   +1 more source

Ectoine and Hydroxyectoine from Halophilic Bacteria Isolated from Traditional Solar Saltern at Pejarakan Village, Buleleng Regency, Bali

Hayati Journal of Biosciences, 2022
The increased use of ectoine and hydroxyectoine in cosmetics and pharmaceuticals has led to the increasing demand for these bioactive compounds. This study aims to investigate the production of ectoine and hydroxyectoine by halophilic bacteria isolated ...
I Putu Parwata, Siti Maryam, I Nyoman Tika   +2 more
doaj   +1 more source

Production and Solubility of Ectoine: Biochemical and Molecular Dynamics Simulation Studies [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
In this study, ectoine is produced by Streptomyces. sp IBRC-M PTCC 10615. Fermentation parameters such as flow regime, gas hold up, mass transfer coefficient, and mixing time were optimized by statistical analysis. Streptomyces.
Soheil Rezazadeh Mofradnia, Reihaneh Ashouri, Najmeh Abtahi, Fatemeh Yazdian, Hamid Rashedi, Mojgan Sheikhpour, Fatemeh Ashrafi   +6 more
doaj   +1 more source

Metabolic engineering of Halomonas elongata: Ectoine secretion is increased by demand and supply driven approaches

Frontiers in Microbiology, 2022
The application of naturally-derived biomolecules in everyday products, replacing conventional synthetic manufacturing, is an ever-increasing market.
Karina Hobmeier, Martin Oppermann, Natalie Stasinski, Andreas Kremling, Katharina Pflüger-Grau, Hans Jörg Kunte, Alberto Marin-Sanguino, Alberto Marin-Sanguino   +7 more
doaj   +1 more source

The biosynthesis of ectoine [PDF]

FEMS Microbiology Letters, 1990
The biosynthetic pathway of the novel compatible solute ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid) was studied in the two extremely halophilic eubacteria Ectothiorhodospira halochloris and Halomonas elongata. The pathway starts with the phosphorylation of l-aspartate and shares its first two enzymatic steps with the biosynthesis
Petra Peters, E.A. Galinski, H.G. Trüper   +2 more
openaire   +2 more sources

Microbial production of ectoine and hydroxyectoine as high-value chemicals

Microbial Cell Factories, 2021
Ectoine and hydroxyectoine as typical representatives of compatible solutes are not only essential for extremophiles to survive in extreme environments, but also widely used in cosmetic and medical industries.
Mengshuang Liu, Hui Liu, Meng Shi, Mingyue Jiang, Lingling Li, Yanning Zheng   +5 more
doaj   +1 more source

Metabolic Engineering of Escherichia coli for Ectoine Production With a Fermentation Strategy of Supplementing the Amino Donor

Frontiers in Bioengineering and Biotechnology, 2022
Ectoine, an osmotic pressure-compensated solute, is used in the food, agriculture, medicine, and cosmetics industries due to its ability to protect macromolecules.
Hao Zhang, Hao Zhang, Zhong Liang, Zhong Liang, Ming Zhao, Ming Zhao, Yanqin Ma, Yanqin Ma, Zhengshan Luo, Zhengshan Luo, Sha Li, Sha Li, Hong Xu, Hong Xu, Hong Xu   +14 more
doaj   +1 more source