Results 161 to 170 of about 139,269 (266)

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Identification of novel macrophages and bone morphogenetic protein signals causing ectopic calcification and impairing muscle regeneration. [PDF]

iScience
Shi L, He Z, Hiraga T, Liu Z, Yamashita T, Iwamoto R, Mizoguchi T, Nakamichi Y, Kubota Y, Udagawa N, Kobayashi Y.   +10 more
europepmc   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Three‐Dimensional Scaffolds for Bone, Soft Tissue, and Periodontal Regeneration

Journal of Periodontal Research, EarlyView.
Three‐dimensional scaffolds offer tissue‐specific control of architecture, mechanics, porosity, and functionalisation to improve bone, soft tissue, and periodontal regeneration. ABSTRACT The oral cavity presents three distinct regenerative challenges: restoration of alveolar bone volume and stability, augmentation of soft mucogingival tissues, and ...
Reuben Staples, Jamil Alayan, Raghavendra Vamsi Anegundi, Marisca Pereira, Saraswat Basu, Sašo Ivanovski   +5 more
wiley   +1 more source

Cell wall integrity and elicitor peptide signaling modulate jasmonic acid‐mediated camalexin production in Arabidopsis

New Phytologist, EarlyView.
Model of the cell wall damage (CWD)‐responsive signaling network leading to camalexin biosynthesis. Summary Plant cell walls constitute dynamic barriers that are essential for defense against pathogens. Beyond a structural role in blocking pathogen infection, innate mechanisms monitor cell wall integrity (CWI) in Arabidopsis thaliana and trigger local ...
Richard Noi Morton, Lian Fleischberger, Joy Debnath, David Biermann, Susanne Mühlbauer, Ahalya Rajendran, Hans‐Henning Kunz, Julien Gronnier, Nora Gigli Bisceglia, Timo Engelsdorf   +9 more
wiley   +1 more source

Impact of the <i>ENPP1</i> mutation on bone mineralization and ectopic calcification: evidence from <i>in vitro</i> and <i>in vivo</i> models. [PDF]

Front Endocrinol (Lausanne)
Wu W, Liu L, Shi Y, Zhang Y, Qiu R, Yan F.   +5 more
europepmc   +1 more source

Oxidative stress is a key regulator of ectopic calcifications in beta-Thalassemia patients

, 2013
A surprisingly high percentage of clinical complications affecting beta-thalassemia (beta-thal) patients is due to ectopic calcification. In these patients, elastic fiber calcification is associated with accumulation of anion superoxide and to ...
QUAGLINO, Daniela, ANNOVI, Giulia, BORALDI, Federica, Cianciulli, Paolo   +3 more
core  

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Bone Marrow-Derived ABCC6 Is an Essential Regulator of Ectopic Calcification In Pseudoxanthoma Elasticum. [PDF]

J Invest Dermatol
Brampton C, Pomozi V, Le Corre Y, Zoll J, Kauffenstein G, Ma C, Hoffmann PR, Martin L, Le Saux O.   +8 more
europepmc   +1 more source

Incretin‐Based Medications in Women and Reproduction: A Systematic Scoping Review and Consensus Guidelines for Clinical Practice

Obesity Reviews, EarlyView.
ABSTRACT Introduction Pregnancy concurrent with incretin‐based medications is contraindicated due to unknown risk of teratogenicity, as is breastfeeding. The aim of this systematic scoping review was to investigate potential risks and benefits of incretin‐based medications in relation to preconception, pregnancy, and postnatal health, and to propose ...
Kate Maslin, Jill Shawe, Sinead Blowers, Michael Ceulemans, Kathryn Hart, Sam Schoenmakers, Amihai Rottenstreich, Heather Hopper, Mojca Jensterle, Angela C. Flynn, Sarah Siegelaar, Annick Bogaerts, Isy Douek, Nicola Heslehurst, Dries Ceulemans, Tricia Tan, Johnathan Pinkney, Martin Whyte, Shahrad Taheri, Roland Devlieger   +19 more
wiley   +1 more source