Results 201 to 210 of about 139,269 (266)

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He   +4 more
wiley   +1 more source

Tendinopathy: Types, Epidemiology, Molecular Mechanisms, and Future Precision‐Oriented Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This review presents tendinopathy as a heterogeneous disorder driven by dynamic interactions among mechanical sensing, inflammation, angiogenesis and innervation, and extracellular matrix remodeling. Integrating clinical phenotypes with imaging, biomarkers, and multi‐omics may enable molecular subtyping and mechanism‐guided interventions, advancing ...
Yang Wu   +4 more
wiley   +1 more source

Gastric Cancer: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin   +6 more
wiley   +1 more source

Chronic, neutrophilic pericarditis with free‐floating intrapericardial mesothelial‐lined fibrous nodules in a cat

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 15‐year‐2‐month‐old, male, neutered domestic shorthair cat was presented for a 1‐week history of increased respiratory effort and declining appetite. Point‐of‐care ultrasound diagnosed tri‐cavitary effusion, and echocardiography revealed the presence of multiple free‐floating hyperechoic nodules within the pericardium.
Maximiliane Gabriele Sehn   +4 more
wiley   +1 more source

Corticosteroid‐augmented interfascial injections for cancer pain management in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 9‐year‐old Rottweiler with metastatic osteosarcoma developed severe episodic pain following forelimb amputation and progression of neoplastic disease. Despite extensive multimodal systemic analgesia, including NSAIDs, gabapentin, amantadine and later amitriptyline, the dog showed persistent vocalisation and touch‐evoked pain in the axillary ...
Zita Julianna Szabo   +3 more
wiley   +1 more source

The Senokine Gas6 Promotes Aortic Valve Calcification Through CaMKII–DRP1–Mediated Terminal Scission of Mitochondrial‐Derived Vesicles

open access: yesAging Cell, Volume 25, Issue 11, November 2026.
In age‐associated calcific aortic valve disease (CAVD), human valve tissues and calcifying human valvular interstitial cells (hVICs) exhibit senescence‐associated features, while calcifying hVICs hypersecrete mitochondrial‐derived vesicles (MDVs). Donut‐shaped mitochondria serve as physical platforms for MDV budding, whereas Gas6 promotes Ca2+–CaMKII ...
Yaoyu Zhang   +17 more
wiley   +1 more source

The Effect of Polycythemia Vera on Pregnancy Complications. The Analysis of an American Population Database With Over 9 Million Deliveries

open access: yesEuropean Journal of Haematology, Volume 117, Issue 5, Page 1249-1257, November 2026.
ABSTRACT Objectives Polycythemia Vera (PV) is characterized by overproduction of erythrocytes, leading to a hypercoagulable state. Evidence regarding associations between PV and pregnancy outcomes is limited. The aim of our study was to provide robust evidence regarding the prevalence of pregnancy complications in women with PV.
Noah Margolese   +5 more
wiley   +1 more source

Associations Between Imaging‐Detected Pulp Calcification and Systemic Diseases: A Systematic Review, Thematic Analysis, and Meta‐Analysis

open access: yesInternational Endodontic Journal, Volume 59, Issue 11, Page 2283-2302, November 2026.
ABSTRACT Background Pulp calcification (PC) is a common imaging finding traditionally attributed to local factors or ageing. However, increasing evidence suggests that it may be associated with broader systemic biological disturbances. Clarifying this association may help determine whether dental pulp findings contribute to the interpretation of ...
José Evando da Silva‐Filho   +2 more
wiley   +1 more source

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