Results 151 to 160 of about 183,658 (172)
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Osteogenesis imperfecta with ectopic mineralizations in dentin and cementum and a COL1A2 mutation

Journal of Human Genetics, 2018
We report a Thai father (patient 1) and his daughter (patient 2) affected with osteogenesis imperfecta type IV and dentinogenesis imperfecta. Both were heterozygous for the c.1451G>A (p.Gly484Glu) mutation in COL1A2. The father, a Thai boxer, had very mild osteogenesis imperfecta with no history of low-trauma bone fractures.
Piranit Nik, Kantaputra   +5 more
openaire   +2 more sources

Inductive specificity of mineralized bone matrix in ectopic osteoclast differentiation

Calcified Tissue International, 1982
The present report describes the first in a series of studies designed to identify the factor or factors responsible for eliciting osteoclast differentiation. Particles of mineralized and demineralized bone, hydroxyapatite (HA), and eggshell were grafted onto the chorioallantoic membranes (CAMs) of chick embryos.
M, Krukowski, A J, Kahn
openaire   +2 more sources

Histomorphometry of ectopic mineralization using undecalcified frozen bone sections

Microscopy Research and Technique, 2018
AbstractTo investigate the correlation between mineral formation and enhanced expressions of some proteins using undecalcified frozen bone sections. Histological studies have revealed that some proteins, such as BMP2, BMPR1A, and Connexin 43, are expressed in and around sites of ectopic ossification.
Ryuji Fujihara   +9 more
openaire   +2 more sources

Effect of Polyvinyl Phosphonates and Ethane Hydroxy Diphosphonate on Mineralization of Ectopic Bone

Chemico-Biological Interactions, 1984
The effects of polymeric polyphosphonate and of ethane hydroxydiphosphonate on the development of ectopic bone were compared at different stages of bone development. The diphosphonate affected bone development at different stages, as reflected by alkaline phosphatase and aryl sulphatase activities, as well as by the creation of calcium ions by bone and
M Anbar
exaly   +3 more sources

Mineral phase in experimental ectopic calcification induced by lead acetate in the rat

Calcified Tissue Research, 1978
Experimental ectopic calcification caused by intravenous injection of lead acetate (Pb−Ac) followed by subcutaneous injection of polymyxin B sulfate (PMX) in the rat was studied by the methods of quantitative chemical analysis and X-ray diffraction analysis using samples freed of organic matter by low temperature ashing (LTA).
Y, Kato, H, Ogura
openaire   +2 more sources

Ectopic mineralization and nutritional hyperparathyroidism in boars.

Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1984
The influence of a high phosphorus (1.5%) and high calcium (2.2%) diet on ectopic mineralization in boars was examined over a four month period. The high phosphorus diet caused metastatic mineralization in the left atrial endocardium in 84% of animals and in the pulmonary and diaphragmatic pleura in 21 and 58% of animals, respectively.
F, Gilka, E A, Sugden
openaire   +1 more source

Small Charged Molecule-Mediated Fibrillar Mineralization: Implications for Ectopic Calcification

ACS Nano
Numerous small biomolecules exist in the human body and play roles in various biological and pathological processes. Small molecules are believed not to induce intrafibrillar mineralization alone. They are required to work in synergy with noncollagenous proteins (NCPs) and their analogs, e.g. polyelectrolytes, for inducing intrafibrillar mineralization,
Ruikang Tang, Baiping Fu, Ying Shi
exaly   +3 more sources

Pseudoxanthoma elasticum: the paradigm of ectopic mineralization disorders – diagnosis and treatment

Expert Review of Dermatology, 2013
Pseudoxanthoma elasticum (PXE) is a prototypic heritable disorder of ectopic mineralization, manifesting with characteristic skin findings, ocular involvement and cardiovascular problems, with considerable morbidity and mortality. The clinical manifestations are of late onset, yet progressive, resulting in loss of visual acuity and occasionally leading
Jouni Uitto, Qiaoli Li, Qiujie Jiang
openaire   +1 more source

Arterial calcification due to CD73 deficiency (ACDC): imaging manifestations of ectopic mineralization

Skeletal Radiology, 2016
Arterial calcification due to CD73 deficiency (ACDC) is a recently identified rare and debilitating adult-onset disorder caused by autosomal recessive NT5E gene mutations. ACDC is characterized by progressive and painful arterial calcifications primarily affecting the lower extremities, as well as calcifications affecting small joint capsules of the ...
Luis Balmore, Gutierrez   +3 more
openaire   +2 more sources

Downregulation of TGF-β1 in Fibro-Adipogenic Progenitors Initiates Muscle Ectopic Mineralization

Journal of Bone and Mineral Research
Abstract In previous studies, we have demonstrated that stress response-induced high glucocorticoid levels could be the underlying cause of traumatic heterotopic ossification (HO), and we have developed a glucocorticoid-induced ectopic mineralization (EM) mouse model by systemic administration of a high dose of dexamethasone (DEX) to ...
Rocky S Tuan, Yingfang Ao, Xiaoqing Hu
exaly   +3 more sources

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