Results 151 to 160 of about 178,374 (209)
Glucagon‐Like Peptide‐1 Receptor Agonist‐Based Agents and Body Composition: Filling More Gaps
ABSTRACT The last 2 decades have seen historic advances in the treatment of obesity. We are entering an era of defining obesity not by weight‐based outcomes but by changes in body composition. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are forming the platform for obesity treatments based on their high level of efficacy. Body composition can
Robert L. Dubin +4 more
wiley +1 more source
Integrative Analysis Uncover the Effects and Multi‐Omics Features of Thigh Muscle Fat Infiltration
Thigh muscle fat infiltration (TMFI), estimated from MRI, is associated with increased mortality and diseases affecting multiple organ systems and mediates the effects of lifestyle factors on health. Multi‐omics analyses delineate the genetic, cellular, transcriptional, proteomic, and metabolic architecture of TMFI.
Yiwei Zhang +12 more
wiley +1 more source
Ectopic pregnancy: a life-threatening gynecological emergency
Osaheni L Lawani, Okechukwu B Anozie, Paul O Ezeonu Department of Obstetrics and Gynecology, Federal Teaching Hospital, Abakaliki, Nigeria Background: Ectopic pregnancy is a life-threatening gynecological emergency, and a significant cause of maternal ...
Anozie OB, Ezeonu PO, Lawani OL
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Abstract Context Primary hyperparathyroidism (PHPT) is often caused by a parathyroid adenoma (PTA). Subtraction scintigraphy with 123I and 99mTc –MIBI SPECT‐CT, and neck ultrasound examination as a hybrid scan (HS) can be used to localize the PTA in order to promote minimally invasive surgery.
Patricia M. Udholm +4 more
wiley +1 more source
ABSTRACT Early clinical development of anticancer drugs traditionally focused on exploring candidate treatments in patients. For instance, due to their cytotoxic action, administration of chemotherapies to healthy volunteers (HVs) for evaluation of their pharmacokinetic profiles was not considered feasible nor ethical from a safety and tolerability ...
Aernout D. van Haarst +5 more
wiley +1 more source
Ectopic mineralization in heart valves: new insights from in vivo and in vitro procalcific models and promising perspectives on noncalcifiable bioengineered valves. [PDF]
Bonetti A, Marchini M, Ortolani F.
europepmc +1 more source
ABSTRACT Aims Tirzepatide is a once‐weekly glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonist (RA) approved for weight management in adults with obesity. Data on older adults remain limited, however. This study aimed to examine tirzepatide's safety and efficacy in adults aged ≥ 65 years with obesity ...
Nasreen Alfaris +6 more
wiley +1 more source
Epidermoid cyst as differential diagnosis for spherical keratoma: What do we know?
Summary This article briefly presents the case of a space‐occupying coronary band mass that raised the question of how one can differentiate between two uncommonly seen but now commonly paired differential diagnoses and prompted a review of the relevant literature.
R. Goodman‐Davis +2 more
wiley +1 more source
Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar +4 more
wiley +1 more source
Isolated bilateral ectopic microspherophakia
André Omgbwa Eballe1, Godefroy Koki2, Emilienne Epée2, Didier Owono2, Lucienne Bella Asumpta2, Côme Ebana Mvogo21Faculty of Medicine and Pharmaceuticals Sciences, University of Douala Cameroon; 2Faculty of Medicine and ...
Emilienne Epée +3 more
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