Results 131 to 140 of about 183,658 (172)

Harnessing genetic variation for grain quality from diverse wheat landraces

New Phytologist, Volume 252, Issue 5, Page 1924-1942, December 2026.
Grain protein content is usually measured on bulk samples, hiding variation between individual grains. We used hyperspectral imaging to predict protein in c. 15 000 single grains from over 500 Watkins wheat landraces grown in two environments, resolving both mean protein content and grain‐to‐grain uniformity.
Luqman B. Safdar, M. John Foulkes, Alix Cornish, Elizabeth D. Goodman, Andrew B. Riche, David Steele, Charlie Philp, Shiva Rahimitanha, Martin Whitworth, Iain R. Searle, Matt Kerton, Malcolm J. Hawkesford, Simon Griffiths, Rahul A. Bhosale, Scott A. Boden, Ian D. Fisk   +15 more
wiley   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, Volume 13, Issue 61, 3 November 2026.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

788 Genetic modifiers for ectopic mineralization: The paradigm of PXE [PDF]

Journal of Investigative Dermatology, 2018
Q. Li, D. Wang, J. Uitto, J.P. Sundberg
openaire   +1 more source

Intranasal Ectopic Tooth in an Adolescent With Unilateral Cleft Lip and Palate: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT A 14‐year‐old male with repaired cleft lip and palate presented with unilateral foul‐smelling nasal discharge, obstruction, and facial pain. CT identified an intranasal ectopic tooth with chronic sinusitis. Surgical removal using a Caldwell Luc approach resulted in symptom resolution.
Mikyas Befekadu Nigusse, Bewuketu Kefyalew Zewudie, Ermias Algawork Kibru, Nuhamin Daniel Kiflemariam, Bemnet Abi Zeleke   +4 more
wiley   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source

Submandibular odontogenic choristoma in a Boer goat

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Submandibular odontogenic choristoma is a rare anomaly in both human and veterinary medicine. A case is described here in a Boer goat used for show, from which the benign growth was surgically removed without complication. This case documents the clinical presentation, diagnostic imaging and histopathology of this anomaly.
Steven E. Edmonds, Rachel M. Bone Relat, Ashley R. Bredenberg, Kyle R. Taylor   +3 more
wiley   +1 more source

The Senokine Gas6 Promotes Aortic Valve Calcification Through CaMKII–DRP1–Mediated Terminal Scission of Mitochondrial‐Derived Vesicles

Aging Cell, Volume 25, Issue 11, November 2026.
In age‐associated calcific aortic valve disease (CAVD), human valve tissues and calcifying human valvular interstitial cells (hVICs) exhibit senescence‐associated features, while calcifying hVICs hypersecrete mitochondrial‐derived vesicles (MDVs). Donut‐shaped mitochondria serve as physical platforms for MDV budding, whereas Gas6 promotes Ca2+–CaMKII ...
Yaoyu Zhang, Jialiang Zhang, Yanjiani Xu, Wenhua Lei, Fei Xu, Junli Li, Zisong Wei, Bo Su, Shuang Liu, Jing Zhou, Hongde Li, Junpeng Ran, Weiya Li, Tuerhongjiang Tuerdi, Xiaojiao Wang, Zhi Fang, Fangyang Huang, Mao Chen   +17 more
wiley   +1 more source

Associations Between Imaging‐Detected Pulp Calcification and Systemic Diseases: A Systematic Review, Thematic Analysis, and Meta‐Analysis

International Endodontic Journal, Volume 59, Issue 11, Page 2283-2302, November 2026.
ABSTRACT Background Pulp calcification (PC) is a common imaging finding traditionally attributed to local factors or ageing. However, increasing evidence suggests that it may be associated with broader systemic biological disturbances. Clarifying this association may help determine whether dental pulp findings contribute to the interpretation of ...
José Evando da Silva‐Filho, Paula Maria da Costa Torres, Eduardo Diogo Gurgel‐Filho   +2 more
wiley   +1 more source

Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues.

, 2005
Pseudoxanthoma elasticum (PXE), characterized by connective tissue mineralization of the skin, eyes, and cardiovascular system, is caused by mutations in the ABCC6 gene.
Choi, H Y, Pulkkinen, L, Uitto, J, Li, K, Jiang, Q J, Matsuzaki, Y, Sundberg, J P, Terlizzi, J, Birk, D E, Fujimoto, N, Klement, J F   +10 more
core   +1 more source