Results 141 to 150 of about 199,968 (239)

Jejunal Ectopic Pancreatic Tissue Rest as Lead Point in Patients with Intussusception: A Rare Case Report and Review of Literature

open access: yesClinical and Experimental Gastroenterology
Worku Mekonnen Sefefe,1 Destaw Biadgie Tesfaw,2 Andualem Dagne Tebikew,2 Assefa Sisay Ayenew,3 Bereket Amare Dencha,4 Temesgen Agegnehu Abebe1 1Department of Surgery, Debre Markos University (DMU), Debre Markos, Amhara, Ethiopia; 2Department of Surgery ...
Sefefe WM   +5 more
doaj  

Recent Development of Endo‐hepatology

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endo‐hepatology is a rapidly evolving field encompassing endoscopic diagnosis and treatment of hepatobiliary diseases, primarily using endoscopic ultrasound (EUS). Since its conceptualization in 2012, the field has expanded dramatically alongside advances in interventional EUS. A landmark 2024 review broadened the concept to include endoscopic
Akira Yamamiya   +3 more
wiley   +1 more source

Integrated single‐cell transcriptomics reveals miR‐941 targets CLDN4 to inhibit malignant progression of thyroid cancer through the PI3K/AKT signaling pathway

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.
The combined single‐cell and functional analysis depicts that miR‐941 targets CLDN4 and activates the regulatory axis that drives the malignancy of thyroid cancer through the PI3K/AKT pathway. Abstract Claudin‐4 (CLDN4), a key tight junction protein, has been implicated in tumor progression; however, its functional role and regulatory mechanisms in ...
Jinghua Zhou   +9 more
wiley   +1 more source

Sex‐Modulated TACSTD2 Methylation and Hormone‐Receptor Axis Interactions in Glioblastoma: Insights Toward Mechanistic Understanding

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
Sex‐stratified analyses of the TCGA and CGGA cohorts have identified promoter‐proximal TACSTD2 CpG sites where methylation shows opposite survival associations in males and females, is independent of copy number, and correlates with TACSTD2 expression.
Tahreem Fatima
wiley   +1 more source

Incretin‐Based Therapies as Cardiometabolic Interventions: Outcome Hierarchy, Receptor‐Network Pharmacology and Phenotype‐Based Clinical Positioning

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10977-10991, December 2026.
ABSTRACT Aims Incretin‐based pharmacotherapy was initially developed to improve glucose‐dependent insulin secretion and glycaemic control in type 2 diabetes, but its clinical interpretation has expanded substantially with cardiovascular outcome trials, kidney outcome data, obesity studies and next‐generation polyagonist development.
Ferenc Sztanek   +3 more
wiley   +1 more source

Effectiveness of Adding GLP‐1 Receptor Agonists to SGLT2 Inhibitor Therapy in Chronic Kidney Disease: A Population Based Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11755-11764, December 2026.
ABSTRACT Background Individually, sodium–glucose co‐transporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have been shown to reduce major kidney and cardiovascular events in patients with chronic kidney disease (CKD). However, evidence supporting combined GLP‐1RA and SGLT2i therapy in this population remains limited.
Hussain Salim   +9 more
wiley   +1 more source

Ferroptosis Suppression by the M6A Reader IGF2BP1 Underlies Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu   +10 more
wiley   +1 more source

Gastric Ectopic Pancreas With Pseudocyst Formation Causing Gastric Outlet Obstruction. [PDF]

open access: yesACG Case Rep J, 2023
Dickerson A   +6 more
europepmc   +1 more source

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