Results 101 to 110 of about 15,580 (252)
Dermatology and TherapyIntroduction Treat-to-target (T2T) strategies have been adopted in atopic dermatitis (AD) management, which defines specific moderate/acceptable and optimal targets for reducing disease severity.
Zhao Wang +6 more
doaj +1 more source
The value of SCORAD and Beyond : towards a standardized evaluation of severity?
, 2004 The clinical scoring systems of atopic dermatitis were analysed and compared. Some biological parameters that can correlate with the clinical score were also reviewed. After the definition of the disease based on validated clinical criteria, the second
C. Gelmetti, C. Colonna
core +1 more source
Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures
Allergy, EarlyView.This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally +6 more
wiley +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
Allergy, EarlyView.ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source
Acta Dermato-VenereologicaIncreasing life expectancy will lead to more elderly people with atopic dermatitis; however, analyses of the impact of atopic dermatitis therapy on the elderly are lacking.
Clara Mathieu +26 more
doaj +1 more source
, 2014 The lack of core outcome sets for atopic eczema (AE) is a major obstacle for advancing evidence-based treatment. The global Harmonising Outcome Measures for Eczema (HOME) initiative has already defined clinical signs, symptoms, quality of life, and long ...
Stefanie Deckert +21 more
core +1 more source
Allergy, EarlyView.ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe +24 more
wiley +1 more source
Frontiers in NeuroscienceBackgroundNeuroimmune interactions provide a rationale for studying somatosensory neuromodulation in inflammatory disorders, but a single clinical observation cannot establish an autonomic mechanism.
Xiaoxue Mei +7 more
doaj +1 more source
Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases
Allergy, EarlyView.ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz +22 more
wiley +1 more source
Allergy, EarlyView.Compartment‐resolved transcriptomic profiling of AD, PsO, and clinically ambiguous AD‐PsO overlap lesions reveals molecular heterogeneity, with overlap lesions showing relative alignment toward AD‐like or PsO‐like patterns. AD‐like alignment is associated with epidermal barrier and dermal neural/sensory pathways, whereas PsO‐like alignment is ...
Jongeun Lee +9 more
wiley +1 more source