Results 111 to 120 of about 15,580 (252)

Evaluation of the measurement properties of symptom measurement instruments for atopic eczema : A systematic review

, 2016
Background: Symptoms have been identified as a core outcome domain for atopic eczema (AE) trials. Various instruments exist to measure symptoms in AE, but they vary in quality and there is a lack of standardization between clinical trials.
Gerbens, L. A. A., Apfelbacher, C. J., Spuls, P. I.,, Svensson, �., Prinsen, C. A C, Zhang, J.,, Chalmers, J. R., Drucker, A. M., Terwee, C. B.,, Limpens, J.,, Prinsen, C. A. C., von Kobyletzki, L. B.,, Prinsen, C. A C,, Chalmers, J. R.,, Limpens, J., Zhang, J., Drucker, A. M.,, Nankervis, H.,, von Kobyletzki, L. B., Gerbens, L. A A, Svensson, Åke,, Terwee, C. B., Nankervis, H., Svensson, Åke, Apfelbacher, C. J.,, Spuls, P. I., Gerbens, L. A A,, The Harmonising Outcome Measures for Eczema (HOME) initiative, Lund University., Svensson, Å.   +29 more
core   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

The effects of Chinese botanical lotion and pimecrolimus cream in the treatment of chronic perianal eczema: a randomized clinical trial

Frontiers in Pharmacology
BackgroundFumigation and sitz-bath therapy are traditional Chinese medicine (TCM) practices that offer unique benefits for managing chronic perianal eczema (CPE).
Lixia Lai, Yanmei Wang, Luping Wen, Shaozhao Wang, Si Chen, Chao Gu, Zeye Zhang   +6 more
doaj   +1 more source

Mapping SCORing of Atopic Dermatitis (SCORAD) and objective SCORAD to the Eczema Area and Severity Index to facilitate large-scale meta-analyses of molecular data

British Journal of Dermatology
We used data from 1501 patients to build mathematical models for mapping between common measures of atopic dermatitis severity, including SCORing of Atopic Dermatitis (SCORAD), objective SCORAD (oSORAD) and the Eczema Area and Severity Index (EASI). These models can be used to facilitate progress in harmonizing patient data across studies, enabling ...
Matthias Hübenthal, Chengliang Dai, Sara J Brown, Luise Heinrich, Barbara Kind, Inken Harder, Jochen Schmitt, Thomas Werfel, Stephan Weidinger   +8 more
openaire   +2 more sources

Supplementary Material for: Prospective, Randomized Study on the Efficacy and Safety of Local UV-Free Blue Light Treatment of Eczema

, 2016
Background: Blue light was shown to reduce the activation of T cells and modulate cytokine release in vitro. Therefore, we investigated the efficacy of blue light in the treatment of eczema.
Merk H.F. (2988648), Liebmann J. (2988645), Pfaff S.C. (2988657), von Felbert V. (2988654), Keemss K. (2988651), Born M. (2988660)   +5 more
core   +1 more source

Real-world efficacy and safety of dupilumab in the treatment of head and neck atopic dermatitis: a retrospective cohort study

Frontiers in Medicine
BackgroundHead and neck atopic dermatitis (HNAD) is a clinically common subtype of AD. While dupilumab is widely used in AD treatment, its efficacy in HNAD is debatable.ObjectiveThis study aimed to evaluate the real-world efficacy and safety of dupilumab
Zifan Li, Junsheng Peng, Ruoxi Yu, Ying Lin, Ying Lin, Ying Lin, Ying Lin   +6 more
doaj   +1 more source

European Guidelines on Eosinophilic Esophagitis: Evidence‐Based Statements and Recommendations for Diagnosis and Management in Children and Adults. Part 1: Diagnosis, Epidemiology and Natural History

Allergy, EarlyView.
The European evidence‐based guidelines on eosinophilic esophagitis (Part 1). This infographic summarizes the methodological framework and core clinical outputs of the updated consensus developed by multidisciplinary experts from EUREOS, EAACI, ESPGHAN, and ESP.
Alfredo J. Lucendo, Javier Molina‐Infante, Ángel Arias, Ulrike von Arnim, Henrik Bergquist, Luc Biedermann, Albert J. Bredenoord, Marie Carlson, Javier Chahuan, Jorge Amil Dias, Thomas Eiwegger, Sara Feo‐Ortega, Sandra L. Garcia‐Dionisio, Matteo Ghisa, Jesús González‐Cervera, Thomas Greuter, Danila Guagnozzi, Carolina Gutiérrez‐Junquera, Lucía Gutiérrez‐Ramírez, Cord Langner, Helen Larsson, Anne Lund Krarup, Salvatore Oliva, Alexandra Papadopoulou, Francesca Racca, Cecilio Santander, Edoardo Vincenzo Savarino, Christoph Schlag, Alain M. Schoepfer, Martin A. Storr, Antonio Tejera‐Muñoz, Noam Zevit, Stephen E. Attwood, Alex Straumann   +33 more
wiley   +1 more source

Clinical Trial: Capsule Sponge as a Non‐Endoscopic Monitoring Tool in Eosinophilic Oesophagitis—A Prospective Real–World Multicentre Study

Alimentary Pharmacology &Therapeutics, EarlyView.
Capsule sponge sampling with Endosign provides a safe, feasible and acceptable alternative to endoscopic biopsy for monitoring eosinophilic oesophagitis. In 164 paired assessments, eosinophil counts on capsule sponge cytology showed a strong correlation with endoscopic biopsy histology.
Rohith Kumar, Ayesha Rai, Kim Shaw, Erzsebet Santa, Francoise Cole, Hyesha McDonald, Pearl Baker, Lisa Mears, Anjan Dhar, Guiomar Moral‐Villarejo, Jacobo Ortiz Fernández‐Sordo, Ashraf Sanduka, Maria O'Donovan, Radina Georgieva, Sarah Killcoyne, Danielle L. Morris   +15 more
wiley   +1 more source

A cosmeceutical formulation based on boswellic acids for the treatment of erythematous eczema and psoriasis

Clinical, Cosmetic and Investigational Dermatology, 2014
Stefano Togni,1 Giada Maramaldi,1 Francesco Di Pierro,2 Massimo Biondi3 1Indena S.p.A., Milan, Italy; 2Velleja Research, Milan, Italy; 3Dermatology Unit, ASL Piacenza, Piacenza, Italy Background: Boswellic acids (BAs) show anti-inflammatory properties ...
Togni S, Maramaldi G, Di Pierro F, Biondi M   +3 more
doaj  

Preliminary Clinical and Mechanistic Evaluation of Traditional Thai Herbal Cream Containing Cannabis sativa and Curcuma longa for Eczema and Psoriasis

Cosmetics
Cannabis sativa and Curcuma longa have traditionally been used for the management of skin disorders; however, scientific evidence supporting their combined topical use in eczema and psoriasis remains limited. To characterize the phytochemical composition,
Julalak Chorachoo Ontong, Chatchai Wattanapiromsakul, Charassri Nualsri, Sudarshan Singh, Popat Mohite, Benjaporn Bourchum, Meadeena Kobmang, Pinyada Subyad, Thanyaphon Pusawiro, Supatina Khan, Nattanon Bunrodchu, Narapat Aunruean, Apiwat Artkaew, Anon Makklay, Thanyaluck Siriyong   +14 more
doaj   +1 more source