Results 91 to 100 of about 15,580 (252)

Optimising the Diagnosis of Sesame Seed Allergy With the Basophil Activation Test

Allergy, EarlyView.
The basophil activation test (using the activation marker CD203c) was the only test able to both exclude and confirm sesame seed allergy with precision. A negative skin prick test to sesame extract or tahini and undetectable IgE to Ses i 1 could not rule out sesame seed allergy.
Ru‐Xin Foong, Irene Bartha, Holly Boyd, Andreina Marques‐Mejias, Suzana Radulovic, Marta Krawiec, Faye Harrison, Malak Eghleilib, Grammatiki Antoneria, Zainab Jama, Matthew Kwok, Vasco Claro, Cristian Ricci, Tom Marrs, Gideon Lack, George Du Toit, Alexandra F. Santos   +16 more
wiley   +1 more source

A Durability Index for Atopic Dermatitis: Indirect Comparison of Lebrikizumab, Dupilumab, and Tralokinumab in Maintaining Efficacy Under Variable Treatment Adherence

Dermatology and Therapy
Introduction Real-world management of moderate-to-severe atopic dermatitis (AD) may involve treatment interruptions. This indirect comparison evaluated the efficacy of lebrikizumab, dupilumab, and tralokinumab monotherapy in achieving week-52 response at
Jonathan I. Silverberg, Alan D. Irvine, Peter Foley, James Del Rosso, Luis Puig, Linda Stein Gold, Masahiro Kamata, Andreas Wollenberg, H. Chih-ho Hong, Chia-Yu Chu, Yousef Binamer, Martin Dossenbach, Marta Casillas, Gaia Gallo, Buelent Akmaz, Kim Rand, Raj Chovatiya   +16 more
doaj   +1 more source

Differences in Itch Quality Between Interleukin-31 and Thymus and Activation-Regulated Chemokine of Japanese Atopic Dermatitis

Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Objective: To elucidate the relationships among various itch qualities, blood biomarkers, and patient-reported outcome measures (PROMs) in atopic dermatitis (AD), we characterized 10 qualities of itch (QoIs) in adult Japanese patients with AD and ...
Yozo Ishiuji, MD, PhD, Minako Ogawa-Tominaga, MS, Michie Katsuta, MD, PhD, Itaru Dekio, MD, PhD, Shiho Kawagoe, Yoko Kobayashi, Yoshimasa Nobeyama, MD, PhD, Budiman Kharma, MD, PhD, Hiroshi Kawasaki, MD, PhD, Toshiya Ebata, MD, PhD, Motoki Morita, PhD, Mitsutoshi Tominaga, PhD, Kenji Takamori, MD, PhD, Akihiko Asahina, MD, PhD   +13 more
doaj   +1 more source

Preventive Application of House Dust Mite‐Sublingual Immunotherapy Induces Blocking Antibodies in Sensitized Preschool Children

Allergy, EarlyView.
HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi, Klara Schmidthaler, Hilal Demir, Justyna Sieber, René Gaupmann, Livia Mia Gona‐Höpler, Christina Bannert, Saskia Gruber, Eleonora Dehlink, Thomas Eiwegger, Alexandra Graf, Barbara Bohle, Zsolt Szépfalusi   +12 more
wiley   +1 more source

A randomized trial of methotrexate vs. azathioprine for severe atopic eczema: a critical appraisal.

, 2012
AIM: Schram et al. aimed to compare the efficacy and safety of methotrexate vs. azathioprine in adults with severe atopic eczema. SETTING AND DESIGN: This single-blind, parallel-group (ratio 1 : 1), randomized controlled trial was conducted in a ...
Batchelor, JM, Patel, AN, Langan, SM
core   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Global Variation in Timing of Allergenic Food Introduction for Food Allergy Prevention: An International Survey of Healthcare Professionals

Allergy, EarlyView.
This study examines the current state of food allergy prevention guideline implementation worldwide, identifying key variables that may explain the observed global variation. Among 731 healthcare professionals across 80 countries, geography and clinical specialty independently drove allergenic food introduction practices, creating an 8.5‐month practice
Agnes Sze‐yin Leung, Elizabeth Huiwen Tham, Kiwako Yamamoto‐Hanada, Derek K. Chu, Matthew Norris, Daria Levina, Daniel Munblit, Lamia Dahdah, Luciana Kase Tanno, Carmen Riggioni, Elsy M. Navarrete‐Rodriguez, Michael E. Levin, Thulja Trikamjee, William Guo, Chun Tong Lei, Chun Pong Lau, Supinda Bunyavanich, Nikolaos G. Papadopoulos, Adnan Custovic, Christina West, Gary Wing‐kin Wong   +20 more
wiley   +1 more source

Baricitinib Improvement Across Regions in Atopic Dermatitis Patients with Baseline Body Surface Area up to 40% and Severe Itch

Dermatology and Therapy
Introduction Patients with moderate-to-severe atopic dermatitis (AD) who are most likely to respond to the Janus kinase (JAK) 1/2 inhibitor baricitinib (BARI) are known to have an impacted body surface area (BSA) ≤ 40% and severe itch (numerical rating ...
José-Manuel Carrascosa, Alessandra Narcisi, Toshifumi Nomura, Sonja Ständer, Christian Vestergaard, Silvia Sabatino, Susanne Grond, Uffe Koppelhus, Mohamed Elrayes, Yun-Fei Chen, Chunyuan Liu, Andreas Wollenberg   +11 more
doaj   +1 more source

Validation of remote atopic dermatitis severity assessment with the Eczema Area and Severity Ondex in children using caregiver-provided photos and videos. [PDF]

Pediatr Dermatol, 2022
Croce EA, Rathouz PJ, Lopes FCPS, Leszczynska M, Diaz LZ, Levy ML, Ruth JS, Varshney P, Rew L, Matsui EC.   +9 more
europepmc   +1 more source

Parental and Healthcare Professional Experiences of Food Allergen Introduction During Complementary Feeding: A Behavioural Theory–Informed Systematic Review

Allergy, EarlyView.
ABSTRACT Background IgE‐mediated food allergy burdens individuals, families and healthcare systems. Randomised controlled trials indicate early introduction and regular consumption of common food allergens in infancy can reduce food allergy risk. Few studies have explored parental and healthcare professional experiences. This systematic review examines
Karen Wright, Amelia Dennis, Luise V. Marino, Stephanie Easton, Samantha Hornsey, Sebastien Pollet, Misbah Primett, Goldie Putrym, Susan Dixon, Helen Reynolds, Anna Rattu, Miriam Santer, Ingrid Muller, Graham Roberts, Ben Ainsworth   +14 more
wiley   +1 more source