Results 201 to 210 of about 67,306 (265)

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

MR Spectroscopy Without Water Suppression Using the Gradient Impulse Response Function. [PDF]

Magn Reson Med
Bacon JB, Jezzard P, Clarke WT.
europepmc   +1 more source

PrEP at the site of action in cisgender and transgender women: A pharmacology study of blood and rectal CD4+ lymphocytes

British Journal of Clinical Pharmacology, EarlyView.
Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie, Megha Srivasta, Edward R. Cachay, Leah Burke, Sara Gianella, Stephen Rawlings, Frank Z. Stanczyk, Craig Sykes, Angela D. M. Kashuba, Jill Blumenthal, Mackenzie L. Cottrell   +10 more
wiley   +1 more source

Multimodal brain MRI and clinical data in olfactory groove meningioma: a prospective data report. [PDF]

Front Radiol
Filimonova E, Pashkov A, Moysak G, Martirosyan A, Kurilov V, Poptsova A, Morozova R, Rzaev J.   +7 more
europepmc   +1 more source

Oseltamivir drug‐disease modelling in infants with influenza virus infection

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Oseltamivir is a commonly used neuraminidase inhibitor for treatment of influenza infection, but little data exist regarding concentration‐response relationships. Methods Pharmacokinetic (PK) and viral dynamic data from an earlier NIAID Collaborative Antiviral Study Group trial in paediatric patients with influenza from 0–23 months of age
Kun Wang, David W. Kimberlin, Richard J. Whitley, Edward P. Acosta, For the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group   +4 more
wiley   +1 more source

A Multi-Site Study of Brief Cognitive-Behavioural Therapy for Eating Disorders for Individuals With BMI ≥ 30. [PDF]

Eur Eat Disord Rev
Dunford A, Kambanis PE, Palmer LP, Graver H, Liu ME, Hillard J, Yee S, Turner H, Breithaupt L, Evans E, Blythe E, White C, Broadley J, Waller G, Eddy KT, Thomas JJ, Becker KR.   +16 more
europepmc   +1 more source

Tests diagnostiques privés offerts directement au consommateur : la vigilance est de mise. [PDF]

CMAJ
McRae AD, Lang ES.
europepmc   +1 more source

A daily three-dimensional dataset of the Kuroshio axis and boundaries in the East China Sea and Luzon Strait. [PDF]

Sci Data
Wang J, Chen X, Mao K, Zhang C.
europepmc   +1 more source

Evaluation of an orthodontic adhesive containing 2 wt% nano-hydroxyapatite synthesized from a biogenic calcium precursor: antibacterial activity, calcium ion concentration, and enamel demineralization. [PDF]

Biomater Investig Dent
Pamungkas GB, Habar EH, Tanumihardja M, Samad R, Stang, Erwansyah E, Hamrun N.   +6 more
europepmc   +1 more source