Results 161 to 170 of about 33,099 (254)

Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri, Ahmad Gharaibeh, Lubika Nkashama, Abdelrahman Abushouk, Osama Abushawer, Amir Mehdizadeh‐Shrifi, Bianca Honnekeri, Cassandra Calabrese, Venu Menon, Pauline Funchain, Patrick Collier, Diego Sadler, Rohit Moudgil   +12 more
wiley   +1 more source

The monoclonal antibody AZD5148 confers broad protection against TcdB-diverse Clostridioides difficile strains in mice. [PDF]

PLoS Pathog
Peritore-Galve FC, Kroh HK, Shupe JA, Ehni AG, Cano Rodríguez R, Kordus SL, Washington MK, Knippel RJ, Stanley AM, Gamson A, Tkaczyk C, Lacy DB.   +11 more
europepmc   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Crossed cerebellar diaschisis in status epilepticus: A systematic review of the literature

Epileptic Disorders, EarlyView.
Abstract Objective Crossed cerebellar diaschisis is a neuroimaging phenomenon observed in various neurological conditions, including status epilepticus. This systematic review aims to summarize the clinical and radiological characteristics of patients developing crossed cerebellar diaschisis following status epilepticus and to discuss potential ...
Payam Tabaee Damavandi, Pilar Bosque‐Varela, Helena Barbosa Horta Santos, Bassam Al‐Fatly, Lukas Machegger, Eugen Trinka, Giorgi Kuchukhidze   +6 more
wiley   +1 more source

Anthrax ET activates Rac1 and RTK signaling to induce F-actin reorganization and endothelial permeability. [PDF]

iScience
Jain P, Guichard A, Moayeri M, Kaduwal S, Mel de Fontenay M, Rousseau I, Leppla SH, Bier E.   +7 more
europepmc   +1 more source

Synchrotron‐generated microbeams as a radiosurgical alternative for drug‐resistant epilepsies: Proof of concept in a mouse model of mesiotemporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens, Camille Beets, Clothilde Courivaud, Sarvenaz Keshmiri, Jean‐François Adam, Paolo Pellicioli, Emmanuel Luc Barbier, Raphaël Serduc, Antoine Depaulis   +8 more
wiley   +1 more source

Delayed Inflammation Occurred Only to VYC-25L After Coinjection of VYC-20L and VYC-25L in an Asian Patient. [PDF]

Plast Reconstr Surg Glob Open
Xiang H, Wei M, Yi P, Ao R, Sun Y.
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Severe Necrotizing Pneumonia Caused by Panton‑Valentine Leukocidin‑Producing Staphylococcus aureus in a Previously Healthy Adult. [PDF]

Cureus
Paudyal P, Bedi P.
europepmc   +1 more source