Results 191 to 200 of about 33,099 (254)

Anti‐CD47 antibody‐decorated and cisplatin‐containing mesoporous silica nanoparticles for targeted chemoimmunotherapy of colorectal cancer in a patient‐derived organoids xenograft model

Interdisciplinary Medicine, EarlyView.
Upon targeted binding to CD47‐overexpressing colorectal cancer (CRC) cells, the nanoparticles disrupt signal regulatory protein α‐CD47 signaling and allow for the restoration of innate immune response by tumor‐associated macrophages (TAMs) against CRC.
Albert Yu, Yibo Hou, Kaibin Huang, Xucan Gao, Rong Zeng, Chaowei Zhu, Chunhui Sun, Guocai Wang, Lei Ye, Shaohua Ma, Tian Meng, Bing Guo, Yubo Zhang, Xiaoyong Dai   +13 more
wiley   +1 more source

Botulinum Toxin Type A for Pediatric Torticollis: A Review of Clinical Research. [PDF]

Toxins (Basel)
Kwon NY, Sung SH, Sung HK.
europepmc   +1 more source

Nanoparticle‐integrated electrostimulation‐responsive biomaterials: Innovations in drug delivery and tissue repair in clinical regenerative medicine

Interdisciplinary Medicine, EarlyView.
Schematic representation of nanoparticle‐integrated electrostimulation‐responsive biomaterials for controlled drug delivery and tissue regeneration. Electroactive scaffolds including conductive polymers, electroresponsive hydrogels, and piezoelectric matrices are shown incorporating therapeutic nanoparticles (such as iron oxide, silver, and carbon ...
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Beyond the Break: Radiologic Diagnosis and Outcomes of Necrotizing Fasciitis Complicating Orthopedic Fractures. [PDF]

Cureus
Kaur K, Zain Ul Abidin M, Rasul S, Mohamed AM, Kalissery Biju Chandrasekhar K, Shehata Abdelmesih SR, H J Alkhazendar J, Ijaz F, Alkhazendar AH, Khalid R, Buch MH.   +10 more
europepmc   +1 more source

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, EarlyView.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source

Myocarditis Triggered by Erysipelas: A Rare Infectious Complication. [PDF]

JACC Case Rep
Wosgien K, O H-Ici D.
europepmc   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Extracorporeal membrane oxygenation combined with prone ventilation for the treatment of high-dose metoprolol and amlodipine poisoning: A case report. [PDF]

Resusc Plus
Zhao Z, Wang B, Liu D, Tao W, Tang H, Wu Z, Zhang X, Fang Z.   +7 more
europepmc   +1 more source

The Individual and Combined Effects of Warming and Atrazine on Lithobates pipiens Phenotypes: Implications for Frog Declines

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Amphibians are the most threatened vertebrate class globally. Climate change, agrochemicals, and/or pathogens and parasites are implicated in contributing to amphibian declines, either singly or in combination. We investigated individual and combined effects of elevated temperatures and atrazine (2.0 μg/L) on Lithobates [formerly Rana] pipiens
Melody J. Gavel, Mark R. Forbes, Derek D. N. Smith, Julia Darabaner, Yol Monica Reyes, Zintis Stasko, David J. Carpenter, Stacey A. Robinson   +7 more
wiley   +1 more source

Evaluation of the Effectiveness of Botulinum Therapy Based on the Anthropometric Characteristics of the Face Using Non-Invasive Thermal Imaging Data. [PDF]

Diagnostics (Basel)
Kytko O, Vasil'ev Y, Emelyanova E, Kutin E, Sarmadian R, Trofimova S, Kondrina I, Moiseenko A, Dydykin S, Rebrova E.   +9 more
europepmc   +1 more source