Results 71 to 80 of about 14,669 (262)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
On Partitioning the Edges of 1-Plane Graphs
, 2016 A 1-plane graph is a graph embedded in the plane such that each edge is crossed at most once. A 1-plane graph is optimal if it has maximum edge density.
Lenhart, William J. +2 more
core +1 more source
Revisiting semistrong edge‐coloring of graphs
Journal of Graph Theory, 2023 AbstractA matching in a graph is semistrong if every edge of has an endvertex of degree one in the subgraph induced by the vertices of . A semistrong edge‐coloring of a graph is a proper edge‐coloring in which every color class induces a semistrong matching.
Borut Lužar +2 more
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Degenerate matchings and edge colorings [PDF]
Discrete Applied Mathematics, 2018 A matching $M$ in a graph $G$ is $r$-degenerate if the subgraph of $G$ induced by the set of vertices incident with an edge in $M$ is $r$-degenerate. Goddard, Hedetniemi, Hedetniemi, and Laskar (Generalized subgraph-restricted matchings in graphs, Discrete Mathematics 293 (2005) 129-138) introduced the notion of acyclic matchings, which coincide with ...
Baste, Julien, Rautenbach, Dieter
openaire +3 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Animation Visualization for Vertex Coloring of Polyhedral Graphs [PDF]
Journal of Systemics, Cybernetics and Informatics, 2013 Vertex coloring of a graph is the assignment of labels to the vertices of the graph so that adjacent vertices have different labels. In the case of polyhedral graphs, the chromatic number is 2, 3, or 4. Edge coloring problem and face coloring problem can
Hidetoshi Nonaka
doaj
Solution of Vizing's Problem on Interchanges for Graphs with Maximum Degree 4 and Related Results [PDF]
, 2014 Let $G$ be a Class 1 graph with maximum degree $4$ and let $t\geq 5$ be an integer. We show that any proper $t$-edge coloring of $G$ can be transformed to any proper $4$-edge coloring of $G$ using only transformations on $2$-colored subgraphs (so-called ...
Asratian, Armen S. +1 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source