Results 71 to 80 of about 1,522,114 (310)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Improved distributed degree splitting and edge coloring [PDF]

open access: yesDistributed computing, 2017
The degree splitting problem requires coloring the edges of a graph red or blue such that each node has almost the same number of edges in each color, up to a small additive discrepancy.
M. Ghaffari   +5 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

M2-Edge Colorings Of Cacti And Graph Joins

open access: yesDiscussiones Mathematicae Graph Theory, 2016
An edge coloring φ of a graph G is called an M2-edge coloring if |φ(v)| ≤ 2 for every vertex v of G, where φ(v) is the set of colors of edges incident with v. Let 𝒦2(G) denote the maximum number of colors used in an M2-edge coloring of G.
Czap Július   +2 more
doaj   +1 more source

Facial rainbow edge-coloring of simple 3-connected plane graphs [PDF]

open access: yesOpuscula Mathematica, 2020
A facial rainbow edge-coloring of a plane graph \(G\) is an edge-coloring such that any two edges receive distinct colors if they lie on a common facial path of \(G\).
Július Czap
doaj   +1 more source

Acyclicity in edge-colored graphs [PDF]

open access: yesDiscrete Mathematics, 2017
A walk $W$ in edge-colored graphs is called properly colored (PC) if every pair of consecutive edges in $W$ is of different color. We introduce and study five types of PC acyclicity in edge-colored graphs such that graphs of PC acyclicity of type $i$ is a proper superset of graphs of acyclicity of type $i+1$, $i=1,2,3,4.$ The first three types are ...
Gutin, Gregory   +4 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A note on compact and compact circular edge-colorings of graphs

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2008
In the paper we study two variants of edge-coloring of edge-weighted graphs, namely compact edge-coloring and circular compact edge-coloring. First, we discuss relations between these two coloring models.
Dariusz Dereniowski, Adam Nadolski
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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