Results 121 to 130 of about 4,789,885 (343)

Design and Implement of Microservice System for Edge Computing

open access: diamond, 2020
Peng Sha   +5 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Cluster Computing and the Power of Edge Recognition

open access: yes, 2005
We study the robustness--the invariance under definition changes--of the cluster class CL#P [HHKW05]. This class contains each #P function that is computed by a balanced Turing machine whose accepting paths always form a cluster with respect to some ...
Hemaspaandra, Lane A.   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

EdgeCNN: Convolutional Neural Network Classification Model with small inputs for Edge Computing [PDF]

open access: green, 2019
Shunzhi Yang   +5 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

A survey on the security technology of edge computing

open access: yes大数据, 2019
With the continuous development of Internet of things applications,a large number of mobile terminal devices participate in service computing.Traditional cloud computing models cannot adapt to the rapid growth of data generated by network edge devices ...
Jie LING   +3 more
doaj  

Resource Scheduling Algorithm for Edge Computing Networks Based on Multi-Objective Optimization

open access: yesApplied Sciences
Edge computing networks represent an emerging technological paradigm that enhances real-time responsiveness for mobile devices by reallocating computational resources from central servers to the network’s edge. This shift enables more efficient computing
Wenrui Liu   +7 more
doaj   +1 more source

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