Results 101 to 110 of about 2,538,869 (297)

Locally computing edge orientations

open access: yesCoRR
We consider the question of orienting the edges in a graph $G$ such that every vertex has bounded out-degree. For graphs of arboricity $α$, there is an orientation in which every vertex has out-degree at most $α$ and, moreover, the best possible maximum out-degree of an orientation is at least $α- 1$.
Mitrović, Slobodan   +2 more
openaire   +5 more sources

An Overview of Edge computing and Role of edge computing in IoT

open access: yes, 2023
: As a high growth of Internet of Everything (IoE) internet connection has been increased a lot which leads to low bandwidth ,less security low privacy in cloud computing model to over come this edge computing technologies have emerged . Edge computing is an emerging paradigm which refers to a range of networks and devices near the user .
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Mobility-Enabled Edge Server Selection for Multi-User Composite Services

open access: yes, 2019
In mobile edge computing, a set of edge servers is geographically deployed near the mobile users such that accessible computing capacities and services can be provided to users with low latency.
Kai Peng   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Intelligent Edge Computing and Machine Learning: A Survey of Optimization and Applications

open access: yes
Intelligent edge machine learning has emerged as a paradigm for deploying smart applications across resource-constrained devices in next-generation network infrastructures.
Andrés L. Suárez-Cetrulo   +3 more
core   +1 more source

Architecture,challenges and applications of edge computing

open access: yes大数据, 2019
Edge computing is a new type of computing models that performs computing tasks at the edge of the network.Compared with cloud computing,it can respond to user’s needs more quickly and reliably.Starting from the shortcomings of cloud computing,the concept
Linzhe LI   +3 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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