Results 81 to 90 of about 4,396,199 (295)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Edge and Cloud Computing in Smart Cities

open access: yesFuture Internet
The evolution of smart cities is intrinsically linked to advancements in computing paradigms that support real-time data processing, intelligent decision-making, and efficient resource utilization.
M. Trigka, Elias Dritsas
semanticscholar   +1 more source

IEEE Access Special Section Editorial: Mobile Edge Computing

open access: yesIEEE Access, 2020
Mobile edge computing (MEC) is emerging as a promising computing architecture by pushing computation and storage closer to end-users with both strategically deployed edge servers and opportunistic available resources.
Yan Zhang   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Towards Edge-Cloud Computing [PDF]

open access: yes2018 IEEE International Conference on Big Data (Big Data), 2018
In this paper, we propose edge-cloud computing as a new framework for organizing the data pipeline functions, i.e., acquisition, processing and analytics, in the Internet of Things systems. Edge-cloud computing consists of three layers, namely smart edge devices, fog computing layer and cloud computing layer.
openaire   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Security of intelligent edge computing:a survey

open access: yesDianxin kexue, 2018
With the rise of edge computing,more and more attentions have been paid to security issues of edge computing.The basic concepts,system architecture and the relationship between edge computing and other computing paradigms were introduced.Then the ...
Xingshuo AN   +4 more
doaj   +2 more sources

Information-Centric Networking With Edge Computing for IoT: Research Challenges and Future Directions

open access: yesIEEE Access, 2018
Cloud computing is a paradigm that offers storage, computation, and software services on demand in the Cloud and far from end users. These services and computations are then extended to the Edge of the network with the Edge computing paradigm.
Rehmat Ullah   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Locally computing edge orientations

open access: yesCoRR
We consider the question of orienting the edges in a graph $G$ such that every vertex has bounded out-degree. For graphs of arboricity $α$, there is an orientation in which every vertex has out-degree at most $α$ and, moreover, the best possible maximum out-degree of an orientation is at least $α- 1$.
Mitrović, Slobodan   +2 more
openaire   +4 more sources

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