Results 51 to 60 of about 980,853 (253)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Bearing thinking of edge computing based on NFV

open access: yesDianxin kexue, 2018
Aiming at introducing edge computing into operator’s network,a bearing and deployment thinking based on NFV was presented.Firstly,the industry development trends of edge computing were introduced.Then the concept,service scenarios and special ...
Yujia LUO, Liang OU, Hong TANG
doaj   +2 more sources

An Overview on Edge Computing Research

open access: yesIEEE Access, 2020
With the rapid development of the Internet of Everything (IoE), the number of smart devices connected to the Internet is increasing, resulting in large-scale data, which has caused problems such as bandwidth load, slow response speed, poor security, and ...
Keyan Cao   +3 more
doaj   +1 more source

Big Data and Fog Computing

open access: yes, 2017
Fog computing serves as a computing layer that sits between the edge devices and the cloud in the network topology. They have more compute capacity than the edge but much less so than cloud data centers.
Simmhan, Yogesh
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cloud native based edge computing: vision and challenges

open access: yes物联网学报, 2021
Cloud native computing, featured by low-cost container technology, well fits edge computing.It was proposed to apply cloud native computing to make edge computing resource management and control transparent to application development and operation ...
Deze ZENG   +3 more
doaj   +2 more sources

Data Security and Privacy-Preserving in Edge Computing Paradigm: Survey and Open Issues

open access: yesIEEE Access, 2018
With the explosive growth of Internet of Things devices and massive data produced at the edge of the network, the traditional centralized cloud computing model has come to a bottleneck due to the bandwidth limitation and resources constraint.
Jiale Zhang   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Online Learning for Offloading and Autoscaling in Energy Harvesting Mobile Edge Computing

open access: yes, 2017
Mobile edge computing (a.k.a. fog computing) has recently emerged to enable in-situ processing of delay-sensitive applications at the edge of mobile networks.
Chen, Lixing, Ren, Shaolei, Xu, Jie
core   +1 more source

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