Results 71 to 80 of about 962,170 (319)

Data Security and Privacy-Preserving in Edge Computing Paradigm: Survey and Open Issues

open access: yesIEEE Access, 2018
With the explosive growth of Internet of Things devices and massive data produced at the edge of the network, the traditional centralized cloud computing model has come to a bottleneck due to the bandwidth limitation and resources constraint.
Jiale Zhang   +4 more
doaj   +1 more source

Joint Service Placement and Request Routing in Multi-cell Mobile Edge Computing Networks

open access: yes, 2019
The proliferation of innovative mobile services such as augmented reality, networked gaming, and autonomous driving has spurred a growing need for low-latency access to computing resources that cannot be met solely by existing centralized cloud systems ...
Llorca, Jaime   +4 more
core   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Edge and Central Cloud Computing: A Perfect Pairing for High Energy Efficiency and Low-latency [PDF]

open access: yes, 2019
In this paper, we study the coexistence and synergy between edge and central cloud computing in a heterogeneous cellular network (HetNet), which contains a multi-antenna macro base station (MBS), multiple multi-antenna small base stations (SBSs) and ...
Hu, Xiaoyan   +5 more
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Computing network:a new multi-access edge computing

open access: yesDianxin kexue, 2019
Edge computing has become an important innovative business model in the 5G era,especially its low latency characteristics,which are considered to be unavailable in traditional solutions.Therefore,edge computing can provide more service capabilities and ...
Bo LEI   +4 more
doaj   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

On the computational complexity of edge concentration

open access: yesDiscrete Applied Mathematics, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Mobile Edge Computing

open access: yes, 2021
Abstract—Latest generation mobile networks aim to use multi-tier heterogeneous cellular networks integrated with cloud computing to provide users with low latency and energy-aware service. However, for high bandwidth and low latency services, edge/fog computing comes into the scenario.
openaire   +1 more source

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