Results 91 to 100 of about 266,197 (292)

The formation of an radial edge electric field due to finite ion orbit width effects is the possible root cause of the H-mode edge

Nuclear Fusion
Full orbit-following simulations of thermal ions show that finite ion-orbit width effects create charge separation near the last closed flux surface (LCFS) which generates a localized radial electric field.
G.J. Kramer, A. Bortolon, A. Diallo, R. Maingi   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A wavelet-based method to measure the toroidal mode number of ELMs [PDF]

, 2009
The high confinement mode regime (H-mode) in tokamaks is accompanied by the occurrence of burst of MHD activity at the plasma edge, so-called edge localized modes (ELMs). Because of the short time scales involved in the ELM crash (on JET typically 0.2 ms)
HASH(0x55aa090db2b8), HASH(0x55aa0932f328), Poli, F. M. (Francesca), Sharapov, S. E. (Sergei E.)   +3 more
core  

Simultaneous access to high normalized density, current, pressure, and confinement in strongly-shaped diverted negative triangularity plasmas

Nuclear Fusion
Strongly-shaped diverted negative triangularity (NT) plasmas in the DIII-D tokamak demonstrate simultaneous access to high normalized density, current, pressure, and confinement.
C. Paz-Soldan, C. Chrystal, P. Lunia, A.O. Nelson, K.E. Thome, M.E. Austin, T.B. Cote, A.W. Hyatt, N. Leuthold, A. Marinoni, T.H. Osborne, M. Pharr, O. Sauter, F. Scotti, T.M. Wilks, H.S. Wilson   +15 more
doaj   +1 more source

Toroidal asymmetries in divertor impurity influxes in NSTX

Nuclear Materials and Energy, 2017
Toroidal asymmetries in divertor carbon and lithium influxes were observed in NSTX, due to toroidal differences in surface composition, tile leading edges, externally-applied three-dimensional (3D) fields and toroidally-localized edge plasma ...
F. Scotti, V.A. Soukhanovskii, J.-W. Ahn, A.G. McLean, R. Kaita   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Surface solitons in quasiperiodic nonlinear photonic lattices

, 2011
We study discrete surface solitons in semi-infinite, one-dimensional, nonlinear (Kerr), quasiperiodic waveguide arrays of the Fibonacci and Aubry-Andr\'e types, and explore different families of localized surface modes, as a function of optical power ...
A. A. Ovchinikov, A. A. Ovchinikov, A. S. Davydov, A. Scott, Alejandro J. Martínez, Mario I. Molina, S. Aubry, T. Dauxois   +7 more
core   +2 more sources

Investigation of LHCD capabilities in I-mode plasma on EAST tokamak

Nuclear Fusion
Improved energy confinement mode (I-mode) regime offers promising confinement characteristics with temperature pedestal and low-confinement mode (L-mode) like particle transport.
C.B. Wu, B.J. Ding, M.H. Li, X.L. Zou, X.M. Zhong, A.D. Liu, Y.Q. Chu, X.H. Wu, S.Y. Lin, Y.F. Jin, E.Z. Li, M. Wang, X.J. Wang, H.Q. Liu, Q. Zang, J.S. Gen, Y.H. Cao, J.L. Chen, W. Sun, H.W. Zhao, G.B. Zhang, W.W. Zhang, X.X. Wang, X.Z. Gong, Y.T. Song, EAST I-mode Working Group, the EAST Team   +26 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Tokamak edge localized mode onset prediction with deep neural network and pedestal turbulence

Nuclear Fusion
A neural network, BES-ELMnet, predicting a quasi-periodic disruptive eruption of the plasma energy and particles known as edge localized mode (ELM) onset is developed with observed pedestal turbulence from the beam emission spectroscopy system in DIII-D.
Semin Joung, David R. Smith, G. McKee, Z. Yan, K. Gill, J. Zimmerman, B. Geiger, R. Coffee, F.H. O’Shea, A. Jalalvand, E. Kolemen   +10 more
doaj   +1 more source