Results 31 to 40 of about 48,614 (262)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Nonlinear localized gap modes in width-modulated Fibonacci lattices

open access: yesResults in Physics, 2022
We address the properties of nonlinear localized gap modes supported by the width-modulated Fibonacci lattices, including their existence and stability. Linear system with the width-modulated Fibonacci lattices has multiple gaps. We find the existence of
Weiwei Su   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Tailoring resonant magnetic perturbation to optimize fast-ion confinement during ELM control in KSTAR

open access: yesNuclear Fusion, 2023
3D resonant magnetic perturbation (RMP) is one promising way to control edge localized modes that can cause excessive material erosion of tokamak first walls.
S.M. Yang   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Effects of edge-localized electron cyclotron current drive on edge-localized mode suppression by resonant magnetic perturbations in DIII-D

open access: yesNuclear Fusion
According to recent DIII-D experiments (Logan et al 2024 Nucl. Fusion 64 014003), injecting edge localized electron cyclotron current drive (ECCD) in the counter-plasma-current (counter- I _p ) direction reduces the n = 3 resonant magnetic perturbation ...
Q.M. Hu, N.C. Logan, Q. Yu, A. Bortolon
doaj   +1 more source

Advanced operation modes relying on core plasma turbulence stabilization in tokamak fusion devices

open access: yesAAPPS Bulletin, 2023
Recent progress of advanced operation modes in tokamaks is addressed focusing upon internal transport barrier (ITB) discharges. These ITB discharges are being considered as one of candidate operation modes in fusion reactors.
Yong-Su Na
doaj   +1 more source

On the onset of type I edge localized modes [PDF]

open access: yesNuclear Fusion, 2009
The affiliation of the first author should be corrected to read G.Y. Antar, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA, Present address: American University of Beirut, Riad El-Solh, Beirut 1107 2020, Lebanon.The following Acknowledgment should be added: This work was supported in part by the US Department of Energy ...
Antar, G. Y.   +5 more
openaire   +3 more sources

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