Results 111 to 120 of about 429,051 (306)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

A remark on the metric dimension in Riemannian manifolds of constant curvature [PDF]

open access: yesAUT Journal of Mathematics and Computing
We compute the metric dimension of Riemannian manifolds of constant curvature. We define the edge weghited metric dimension of the geodesic graphs in Riemannian manifolds and we show that each complete geodesic graph $G=(V,E)$ embedded in a Riemannian ...
Shiva Heidarkhani Gilani   +2 more
doaj   +1 more source

Minimum d-dimensional arrangement with fixed points

open access: yes, 2013
In the Minimum $d$-Dimensional Arrangement Problem (d-dimAP) we are given a graph with edge weights, and the goal is to find a 1-1 map of the vertices into $\mathbb{Z}^d$ (for some fixed dimension $d\geq 1$) minimizing the total weighted stretch of the ...
Gupta, Anupam, Sidiropoulos, Anastasios
core   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Double resolvability parameters of fosmidomycin anti-malaria drug and exchange property

open access: yesHeliyon
The practical and theoretical significance of the resolvability parameter makes it an important factor, particularly in the context of network analysis.
Rashad Ismail   +3 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Double edge resolving set and exchange property for nanosheet structure

open access: yesHeliyon
The exploration of edge metric dimension and its applications has been an ongoing discussion, particularly in the context of nanosheet graphs formed from the octagonal grid. Edge metric dimension is a concept that involves uniquely identifying the entire
Ali N.A. Koam   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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