Results 71 to 80 of about 22,588 (272)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Metric dimension and zero forcing number of two families of line graphs [PDF]

, 2012
summary:Zero forcing number has recently become an interesting graph parameter studied in its own right since its introduction by the “AIM Minimum Rank–Special Graphs Work Group”, whereas metric dimension is a well-known graph parameter.
Cong X. Kang, Linda Eroh, Yi, Eunjeong, Eunjeong Yi, Eroh, Linda, Kang, Cong X.   +5 more
core   +1 more source

Double resolvability parameters of fosmidomycin anti-malaria drug and exchange property

Heliyon
The practical and theoretical significance of the resolvability parameter makes it an important factor, particularly in the context of network analysis.
Rashad Ismail, Sikander Ali, Muhammad Azeem, Manzoor Ahmad Zahid   +3 more
doaj   +1 more source

On the Edge Resolvability of Double Generalized Petersen Graphs

Journal of Mathematics, 2022
For a connected graph G=VG,EG, let v∈VG be a vertex and e=uw ∈EG be an edge. The distance between the vertex v and the edge e is given by dGe,v=mindGu,v,dGw,v. A vertex w∈VG distinguishes two edges e1,e2∈EG if dGw,e1≠dGw,e2.
Tanveer Iqbal, Muhammad Rafiq, Muhammad Naeem Azhar, Muhammad Salman, Imran Khalid   +4 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Edge metric dimension of some Cartesian product of graphs

The edge metric dimension edim(G)of a connected graph G is the minimum cardinality of a set S of vertices such that each edge is uniquely determined by its distance from the vertices of the set S. In this work, the edge metric dimension of the prism over
T., Reji, Saritha Chandran C, Chandran C., Saritha   +2 more
core   +1 more source

Edge Resolvability in Generalized Petersen Graphs

, 2023
The generalized Petersen graphs are a type of cubic graph formed by connecting the vertices of a regular polygon to the corresponding vertices of a star polygon. This graph has many interesting graph properties. As a result, it has been widely researched.
Shreefa O. Hilali, Syed Ahtsham Ul Haq Bokhary, Ameni Gargouri, Muhammad Naeem Azhar, Tanveer Iqbal, Mohammed Alhagyan   +5 more
core   +1 more source

Double edge resolving set and exchange property for nanosheet structure

Heliyon
The exploration of edge metric dimension and its applications has been an ongoing discussion, particularly in the context of nanosheet graphs formed from the octagonal grid. Edge metric dimension is a concept that involves uniquely identifying the entire
Ali N.A. Koam, Ali Ahmad, Sikander Ali, Muhammad Kamran Jamil, Muhammad Azeem   +4 more
doaj   +1 more source