Results 81 to 90 of about 254,578 (267)

Double resolvability parameters of fosmidomycin anti-malaria drug and exchange property

Heliyon
The practical and theoretical significance of the resolvability parameter makes it an important factor, particularly in the context of network analysis.
Rashad Ismail, Sikander Ali, Muhammad Azeem, Manzoor Ahmad Zahid   +3 more
doaj   +1 more source

Algebraic and tropical curves: comparing their moduli spaces [PDF]

, 2011
We construct the moduli space for equivalence classes of n-pointed tropical curves of genus g, together with its compactification given by weighted tropical curves, and establish some of its basic topological properties.
Caporaso, Lucia
core  

Dimensionality of social networks using motifs and eigenvalues

, 2014
We consider the dimensionality of social networks, and develop experiments aimed at predicting that dimension. We find that a social network model with nodes and links sampled from an $m$-dimensional metric space with power-law distributed influence ...
Bonato, Anthony, Gleich, David F., Kim, Myunghwan, Mitsche, Dieter, Prałat, Paweł, Tian, Amanda, Young, Stephen J.   +6 more
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Double edge resolving set and exchange property for nanosheet structure

Heliyon
The exploration of edge metric dimension and its applications has been an ongoing discussion, particularly in the context of nanosheet graphs formed from the octagonal grid. Edge metric dimension is a concept that involves uniquely identifying the entire
Ali N.A. Koam, Ali Ahmad, Sikander Ali, Muhammad Kamran Jamil, Muhammad Azeem   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Exploring metric dimension of nanosheets, nanotubes, and nanotori of SiO2.

PLoS ONE
This work investigates the metric dimension (MD) and edge metric dimension (EMD) of SiO2 nanostructures, specifically nanosheets, nanotubes, and nanotorii.
Umar Farooq, Wasim Abbas, Faryal Chaudhry, Muhammad Azeem, Bandar Almohsen   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Edge Metric Dimension of Silicate Networks

Metric dimension is an essential parameter in graph theory that aids in addressing issues pertaining to information retrieval, localization, network design, and chemistry through the identification of the least possible number of elements necessary to identify the distances between vertices in a graph uniquely. A variant of metric dimension, called the
Prabhu, S., Jenifer Janany, T
openaire   +2 more sources