Results 81 to 90 of about 1,081,243 (285)

Termination of violated contract

, 2020
I have choose the termination of a violated contract as a topic of my thesis. I decided to disclose the theoretical and practical problems arising in connection with the functioning of the institution of termination of a violated contract in German ...
Konnova, Kristina
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Effect of the doping gradient of 4H-SiC aluminum-implanted floating field rings for edge termination

Discover Electronics
4 H-silicon carbide (4 H-SiC) has been investigated and utilized for power semiconductor devices because of its wider bandgap than silicon (Si) and hence higher critical electric field and breakdown voltage.
Keng-Ming Liu, Wei-Zhi Lin, Wen-Hao Yang
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Noncollinear magnetism and half-metallicity in biased bilayer zigzag graphene nanoribbons

New Journal of Physics, 2013
In this paper we study the edge polarizations and their consequences for a biased Bernal stacked bilayer graphene nanoribbon with zigzag termination. The magnetic states are classified according to the interlayer and intralayer couplings between the edge
Lihua Pan, Jin An, Yong-Jun Liu
doaj   +1 more source

Mobile termination, network externalities, and consumer expectations [PDF]

We re-examine the literature on mobile termination in the presence of network externalities. Externalities arise when firms discriminate between on- and off-net calls or when subscription demand is elastic.
Hurkens, Sjaak, Lopez, Angel
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Improved radiation detectors on 4H-SiC epilayers by edge termination

, 2016
We report the development of an edge termination by depositing thin Si3N4 passivating film on 4H-SiC epilayer based radiation detector. The edge termination method is shown to be very effective for improving both the detector leakage current and ...
Krishna C. Mandal, Pak, Rahmi O., Mandal, Krishna C., Cihan Oner, Rahmi O. Pak, Öner, Cihan, Chowdhury, Towhid A., Mannan, Mohammad A., Towhid A. Chowdhury   +8 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Variability of MHD instabilities in benign termination of high-current runaway electron beams in the JET and DIII-D tokamaks

Nuclear Fusion
Benign termination, in which magnetohydrodynamic (MHD) instabilities deconfine runaway electrons (REs) following hydrogenic injections, is a promising strategy for mitigating dangerous RE loads after disruptions.
C.F.B. Zimmermann, C. Paz-Soldan, G. Su, C. Reux, A.F. Battey, O. Ficker, S.N. Gerasimov, C.J. Hansen, S. Jachmich, A. Lvovskiy, J. Puchmayr, N. Schoonheere, U. Sheikh, I.G. Stewart, G. Szepesi, JET Contributors, the EUROfusion Tokamak Exploitation Team   +16 more
doaj   +1 more source