Results 131 to 140 of about 2,720,692 (363)
Correction to Van Pham et al’s original article "Using text-matching software in educational science research: Research results from 18 universities in Vietnam". DOI: 10.3897/ese.2023.e107484 [PDF]
European Science Editing
doaj +3 more sources
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The article describes the records in ancient manuscripts containing Azbukovnik, provides a scientific evaluation of such records. Their typological classification in the XVII century manuscripts is given.
doaj
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Cognitive Demand and Cognitive Effort in Post-Editing
The pause to word ratio, the number of pauses per word in a post-edited MT segment, is an indicator of cognitive effort in post-editing (Lacruz and Shreve, 2014). We investigate how low the pause threshold can reasonably be taken, and we propose that 300
Michael Denkowski (5362163) +2 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
DNA sequencing of drug-resistant mammalian cells and clustered, regularly interspaced short palindromic repeats (CRISPR)-Cas9 genome editing to identify drug targets [PDF]
openalex +1 more source
Etienne van Heerden: Mooi loop met die woorde!
The literary press received Etienne van Heerden’s recent novel In stede van die liefde (Instead of love; In cities of love, 2005) positively. The Afrikaans cultural organisation, the ATKV (Afrikaanse Taal- en Kultuurvereniging), for instance awarded the ...
H. P. Grebe
doaj
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source

