Results 31 to 40 of about 8,846 (122)

Los polimorfismos de ITPA no predicen un riesgo adicional más allá de TPMT y NUDT15 para citopenia inducida por tiopurina en la enfermedad inflamatoria intestinal

open access: yesRevista de Gastroenterología de México
Resumen: Introducción y objetivos: La leucopenia relacionada con tiopurina está asociada con polimorfismos en la tiopurina metiltransferasa (TPMT, por sus siglas en inglés) y con el gen NUDT15. Sin embargo, estos polimorfismos explican solo una fracción
A. Jena   +8 more
doaj   +1 more source

Social Determinants of Sepsis Mortality in the United States: A Retrospective, Epidemiologic Analysis

open access: yesWorld Medical &Health Policy, Volume 17, Issue 4, Page 823-830, December 2025.
ABSTRACT Sepsis is a leading cause of mortality in the United States, with over 350,000 deaths annually, yet the contribution of neighborhood‐level social determinants of health (SDoH) remains underexplored. We conducted a retrospective analysis of 4.4 million hospitalized patients with sepsis, identified using ICD‐10 codes, leveraging de‐identified ...
Ahad Khaleghi Ardabili   +3 more
wiley   +1 more source

ESTADO ACTUAL DE LA EDUCACIÓN MÉDICA EN COLOMBIA

open access: yesMedicina, 2015
<p>Con el objeto de expresar algunos conceptos referentes a la Educación Médica Continuada (EMC) y al estado actual de la educación médica en nuestro país, se ha preparado este documento, teniendo en cuenta los conceptos emitidos en la Academia ...
Eduardo Álvarez Peñalosa   +1 more
doaj  

Conceptualization of Health Nationalism and Glocalization of Health Policy: Barriers and Chances for Global Public Health

open access: yesWorld Medical &Health Policy, Volume 17, Issue 4, Page 831-853, December 2025.
ABSTRACT This article aims to sort out the meaning of the term “health nationalism,” operationalize this term and analyze this phenomenon in opposition to the cosmopolitan health policy model. Here, health nationalism is treated as a serious obstacle to access to healthcare and a cultural‐ideological barrier to equity in global public health. Two ideal
Piotr Żuk, Paweł Żuk
wiley   +1 more source

The Structure of Nitro‐ and Polynitropyrazoles: X‐Ray Crystallography Versus Theoretical Calculations

open access: yesAsian Journal of Organic Chemistry, Volume 14, Issue 10, October 2025.
Abstract This publication presents the geometries of 157 nitro‐ and polynitropyrazoles. Among these, 109 compounds were theoretically studied using mainly the B3LYP/6–311++G(d,p) level of theory. Three‐parameter Lee‐Yang‐Parr (B3LYP) is a density functional theory (DFT) method widely used in computational chemistry and constitutes an acceptable ...
Rosa M. Claramunt   +3 more
wiley   +1 more source

Avances del Modelo Educativo para Desarrollar Actividades Profesionales Confiables (MEDAPROC)☆

open access: yesEducación Médica, 2018
Resumen: El Modelo Educativo para Desarrollar Actividades Profesionales Confiables (MEDAPROC) surge como respuesta a la implementación de la educación basada en competencias.
Alicia Hamui-Sutton   +5 more
doaj   +1 more source

Escribir en comunidad: Construcción de relaciones y responsabilidad en la producción de conocimiento

open access: yesAmerican Anthropologist, Volume 127, Issue 3, Page 447-465, September 2025.
ABSTRACT As anthropology reckons with its past, present, and future, anthropologists increasingly seek to challenge inequities within the discipline and academia more broadly. Anthropology, regardless of subdiscipline, is a social endeavor. Yet research often remains an isolating (though not necessarily solitary) process, even within research teams and
Jordi Armani Rivera Prince   +16 more
wiley   +1 more source

Comparison of Globorisk, SCORE2, and PREVENT in the Stratification of Cardiovascular Risk and its Relationship with End‐Organ Damage Among Adults With Arterial Hypertension

open access: yesThe Journal of Clinical Hypertension, Volume 27, Issue 8, August 2025.
ABSTRACT Arterial hypertension often coexists with comorbidities that increase vascular damage. Although the primary goal is to reduce cardiovascular risk, the available risk scores can produce varying estimates. Here, we aim to compare the prevalence of cardiovascular risk categories using three equations (Globorisk, SCORE2, and PREVENT) in adults ...
Silvia Palomo‐Piñón   +12 more
wiley   +1 more source

ITPA polymorphisms do not predict additional risk beyond TPMT and NUDT15 for thiopurine-induced cytopenia in inflammatory bowel disease

open access: yesRevista de Gastroenterología de México (English Edition)
Introduction and aim: Thiopurine-related leukopenia is associated with polymorphisms in the thiopurine methyltransferase (TPMT) and nucleoside diphosphate-linked moiety X type motif 15 (NUDT15) genes.
A. Jena   +8 more
doaj   +1 more source

Differences of the 6N and 6J Substrains of C57BL/6 Mice in the Development of Experimental Autoimmune Encephalomyelitis

open access: yesMedComm, Volume 6, Issue 7, July 2025.
The 6J substrain exhibits more severe EAE than 6N, with increased macrophages, CD8+, and B cells in the CNS, as well as a higher proinflammatory profile and lower anti‐inflammatory profile, correlating with differences in microbial taxa. ABSTRACT Multiple sclerosis (MS) is an autoimmune disease causing neuroinflammation and demyelination in the central
Ana Isabel Álvarez‐López   +7 more
wiley   +1 more source

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