Results 21 to 30 of about 8,846 (122)

Exposure to Gestational Intermittent Hypoxia Does Not Impair the Metabolic Function or Accelerate the Biological Ageing Process of Offspring of Either Sex

Journal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez, Margarida B. Almeida, Joana F. Sacramento, Elena Olea, Jesus Prieto‐Lloret, Asuncion Rocher, Silvia V. Conde   +6 more
wiley   +1 more source

Informed Consent as a Human Right in the Inter‐American Human Rights System (IAHRS)

Developing World Bioethics, Volume 26, Issue 1, Page 11-16, March 2026.
ABSTRACT Informed consent is presented as a fundamental right and principle in modern medical practice. It involves obtaining permission from a patient before any medical procedure, treatment, or research protocol. Although not explicitly recognized as a standalone right in international human rights instruments, informed consent in healthcare is ...
Diana Rocío Bernal‐Camargo, Ana Isabel Gómez–Córdoba   +1 more
wiley   +1 more source

Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies

Clinical Genetics, Volume 109, Issue 2, Page 305-315, February 2026.
Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome. ABSTRACT Ciliopathies are rare genetic disorders characterized by significant genetic and phenotypic variability.
Lucile Boutaud, Chunmei Li, Candice Moncler, Laure Verlin, Meriem Garfa‐Traoré, Nicolas Bourgon, Dhruvin Akbari, Jeanne Porée, Valentina Serpieri, Marine Panza, Lynda Haddad, Patrick Nitschké, Jacqueline Aziza, Cristina Matt, Enza Maria Valente, Patricia Gargallo, Charlotte Dubucs, Tania Attié‐Bitach, Michel R. Leroux, Sophie Thomas   +19 more
wiley   +1 more source

Structural and functional dissection of the WH2/DAD motif of INF2, a formin linked to human inherited degenerative disorders

The FEBS Journal, Volume 293, Issue 3, Page 825-841, February 2026.
The INF2 WH2/DAD domain, composed of hydrophobic and basic regions, forms a single α‐helix in solution. The hydrophobic segment is essential for INF2 function, as its deletion disrupts actin dynamics and causes nuclear abnormalities, like those seen in pathogenic INF2 DID variants. In contrast, natural INF2 WH2/DAD variants found in patients with renal
Leticia Labat‐de‐Hoz, Laura Fernández‐Martín, Paula Morales, Isabel Correas, María Ángeles Jiménez, Miguel Angel Alonso   +5 more
wiley   +1 more source

A Computational Study of the NMR Chemical Shifts of Polynitropyrazoles

Magnetic Resonance in Chemistry, Volume 64, Issue 1, Page 97-113, January 2026.
The 1H, 13C, 15N, and 17O chemical shifts of 91 nitro‐1H‐pyrazoles at GIAO/B3LYP/6‐311++G(d,p) level. The calculated chemical shifts were compared with available experimental data using an empirical equation that relates absolute shieldings to chemical shifts.
Arturo Alcorta, Rosa M. Claramunt, José Elguero, Ibon Alkorta   +3 more
wiley   +1 more source

Update and Comparative Analysis of Food Environment Policies in Mexico: Implementation of the Healthy Food Environment Policy Index in 2016 and 2024

Obesity Reviews, Volume 27, Issue 1, Page 1-15, January 2026.
ABSTRACT Introduction Mexico faces a public health crisis due to the rising prevalence of obesity and noncommunicable diseases, primarily driven by unhealthy food environments. Objective To conduct a second implementation of the Food Environment Policy Index in Mexico to assess policy implementation levels related to healthy food environments and to ...
Ana Munguía, Yatziri Ayvar‐Gama, Vania Lara‐Mejía, Regina Durán, Claudia Nieto, Estefania Rodríguez, Lizbeth Tolentino‐Mayo, Anayancin Acuña‐Ruiz, Evelia Apolinar‐Jiménez, Armando Hazael Ayala‐Román, Carolina Batis, Victoria Eugenia Bolado‐García, Verónica Doré Castillo‐García, Alejandra Contreras‐Manzano, Carlos Cruz‐Casarrubias, Rebeca Cruz‐Santacruz, Anabel Fiorella Espinosa‐De Candido, Héctor Esquivias‐Zavala, Ileana Guadalupe Fajardo‐Niquete, Mario Efraín Flores‐Aldana, Ana Laura González‐Alejo, Hilda María Jiménez‐Acevedo, Ana Larrañaga‐Flota, Mercedes López‐Martínez, Paulina Magaña‐Carbajal, Sophia Eugenia Martínez‐Vázquez, Catalina Medina, Mildred Moreno‐Villanueva, Ángel Pedraza‐López, Vivian Pérez‐Jiménez, Rafael Regla‐Aguirre, Alicia Elizabeth Robledo‐Galván, Ana Gabriela Romero‐Juárez, Guadalupe Ruiz‐Vivanco, Janine Sagaceta‐Mejía, Mariana Saldivar‐Frausto, Jaime Salvador‐Moysén, Fabiola Sánchez‐Meza, Cuauhtémoc Sandoval‐Salazar, Loredana Tavano‐Colaizzi, Mishel Unar‐Munguía, Javier Villanueva‐Sánchez, Ma. Elena Villarreal‐Arce, Simón Barquera   +43 more
wiley   +1 more source

Impact of the endoscopic teaching process on colonic adenoma detection

Revista de Gastroenterología de México (English Edition), 2014
Background: There has been little reported experience in the Latin American hospital setting in relation to the impact of the endoscopic training process on colonoscopy quality.
J.S. Lasa, R. Moore, A.D. Peralta, G. Dima, I. Zubiaurre, M. Arguello, M. Senderovsky, L. Moretti, A. Avagnina, L. Soifer   +9 more
doaj   +1 more source

In Vitro Effects of Cabazitaxel and Menadione on Cell Growth, Metabolism, and Transcriptomic Profile of Human Prostate Cancer Cell Lines

Prostate Cancer, Volume 2026, Issue 1, 2026.
Cabazitaxel is a second‐generation semisynthetic taxane approved for the treatment of prostate cancer. Vitamin K, an essential nutrient involved in blood coagulation and bone metabolism, has also been shown to have antineoplastic effects. However, no information is currently available regarding the combinatorial effects of cabazitaxel and menadione ...
Ana Laura Gómez-Rosas, Mayel Chirinos, Nancy Noyola-Martínez, Mariana Segovia-Mendoza, Nayeli Torres-Ramírez, Sandra Romero-Córdoba, Lilia G. Noriega, Mitzi García-Olivares, Fernando Larrea, David Barrera, Mohd Farhan   +10 more
wiley   +1 more source

Biopsia prostática randomizada: ¿influye el número de muestras y el valor del PSA para la detección del cáncer prostático?

Revista Argentina de Radiología, 2016
Objetivo: Determinar si la realización de un mayor número de muestras según el valor del antígeno prostático específico (PSA) incrementa la detección del cáncer prostático (CaP). Materiales y métodos: Se estudió transversalmente a 994 pacientes sometidos
S. Kozima, J. Costanza, S. Cubillos, J.D. Espitaleta, J. Hernández Pinzón, J.C. Gallo, N. Larrañaga   +6 more
doaj   +1 more source

Prospective Longitudinal Cohort of Argentinean Patients with Progressive Supranuclear Palsy: A Platform for Epidemiological and Translational Research

Alzheimer's &Dementia, Volume 21, Issue S6, December 2025.
Abstract Background Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are two neurodegenerative disorders that manifest disabling postural instability, parkinsonism, cognitive impairment and falls with brain neurofibrillary tangle lesions containing 4‐repeat tau protein. The prevalence is 6/100,000 inhabitants but estimated only from
Blas Couto, María Jose Angel Pinto, Maria‐Elena Avale, Tomas Falzone, Oscar Gershanik, Anabel Chade, Gabriel Mizraji, Maria Eugenia Gonzalez‐Toledo, Maria Peralta, Gonzalo Gomez‐Arevalo, Monica Mezmezian, Connie Marras, Gustavo Sevlever   +12 more
wiley   +1 more source