Results 71 to 80 of about 9,487,017 (308)

Book Review ~ Delivering Digitally: Managing the transition to the knowledge media. Edited by A. Inglis, P. Ling, and V. Joosten

International Review of Research in Open and Distributed Learning, 2002
We know that significant organizational change must have roots both at the top of an organization and “in the trenches” amongst those who must implement the change.
Terry Anderson, Canada Research Chair in Distance Education
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Editorial ~ CIDER is Born

International Review of Research in Open and Distributed Learning, 2004
With significant male trepidation, I want to share a birth story with IRRODL readers. This month, after a seemingly endless gestation, the Canadian Institute for Distance Education Research (CIDER) was born. Like most births, this new presence began with
Terry Anderson, Canada Research Chair in Distance Education
doaj  

Factors Affecting the Participation of the Deaf and Hard of Hearing in e-Learning and Their Satisfaction: A Quantitative Study

International Review of Research in Open and Distributed Learning, 2017
Today the digital divide is measured not so much by access to the internet but by people's ability to interact in cyberspace, which calls for specific digital communication skills.
Emilio Ferreiro Lago, Sara Osuna Acedo
doaj   +1 more source

Student Attitudes Towards Online Education during the COVID-19 Viral Outbreak of 2020: Distance Learning in a Time of Social Distance

International journal of technology in education and science, 2020
In this paper, undergraduate student attitudes towards rapidly shifting to an entirely online learning environment were assessed due to COVID-19. In addition, surveys on perceptions about misinformation in media, overall anxiety towards distance learning,
S. Unger, William Meiran
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Editorial ~ Open Access in Action!

International Review of Research in Open and Distributed Learning, 2006
Mid 2006 finds the academic research community engaged in an ideological and fiscal war related to Open Access publishing. Open Access requires that the full text of publications be made available at no cost to anyone on the open Internet.
Terry Anderson, Canada Research Chair in Distance Education
doaj  

Professional task-based curriculum development for distance education practitioners at master’s level: A design-based research

International Review of Research in Open and Distributed Learning, 2015
Curriculum development for distance education (DE) practitioners is more and more focusing on practical requirements and competence development. Delphi and DACUM methods have been used at some universities.
Xiaoying Feng, Guangxin Lu, Zhihong Yao
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Using Web-Based, Group Communication Systems to Support Case Study Learning at a Distance

International Review of Research in Open and Distributed Learning, 2002
This study explored the capacity of Web-based, group communication systems to support case-based teaching and learning. Eleven graduate students studying at a distance were divided into three groups to collaborate on a case study using either a ...
Liam Rourke, Terry Anderson, Canada Research Chair in Distance Education   +1 more
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