Results 31 to 40 of about 2,405,068 (309)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Examining Service-Learning in a Graduate Physical Education Teacher Education Course

Journal of the Scholarship of Teaching and Learning, 2012
This study was designed to explore the impact of service-learning on graduate physical education teacher education students. Social-Cognitive Theory (Bandura, 1986; 1999) served as the framework to examine graduate student’s experiences in a service ...
Karen S. Meaney, Jeff M. Housman, Arnoldo Cavazos, Michelle L. Wilcox   +3 more
doaj   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Douglass, Malcolm Paul [PDF]

, 2020
University of California, Los Angeles, English, Ph.D. 1981 Claremont Graduate University, Education, MA 1976 Amherst College, English, BA 1974https://scholarworks.sjsu.edu/erfa_bios/1288/thumbnail ...
San Jose State University
core   +1 more source

Entrustable Professional Activities for Pathology

Academic Pathology, 2017
Competency-based medical education has evolved over the past decades to include the Accreditation Council for Graduate Medical Education Accreditation System of resident evaluation based on the Milestones project.
Cindy B. McCloskey MD, Ronald E. Domen MD, Richard M. Conran MD, PhD, JD, Robert D. Hoffman MD, PhD, Miriam D. Post MD, Mark D. Brissette MD, Dita A. Gratzinger MD, PhD, Patricia M. Raciti MD, David A. Cohen MD, Cory A. Roberts MD, Amyn M. Rojiani MD, PhD, Christina S. Kong MD, Jo Elle G. Peterson MD, Kristen Johnson PhD, Sue Plath MA, Suzanne Zein-Eldin Powell MD   +15 more
doaj   +1 more source

Curriculum Development of Educational Technology Graduate Degree with a focus on Special Education in Iran [PDF]

پژوهش در نظام‌های آموزشی, 2018
The aim of this study was to develop a graduate degree in educational technology curriculum with a focus on special education in Iran. The method of research was descriptive-analytic and compatible with Brady method.
Esmaeil Zaraii Zavaraki
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Chasing graduate jobs? [PDF]

, 2011
This paper examines empirically the relationship between under-employment and migration amongst five cohorts of graduates of Scottish higher education institutions with micro-data collected by the Higher Education Statistical Agency.
Mosca, Irene, Wright, Robert
core   +5 more sources