Results 61 to 70 of about 20,645,859 (299)

Higher Education Earnings Premium: Value, Variation, and Trends [PDF]

open access: yes, 2014
Overall, people with a college education do better in the labor market than people with no education beyond high school. Higher levels of education correspond, on average, to higher levels of employment and higher wages.
Sandy Baum
core   +2 more sources

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Pathways to Higher Education [PDF]

open access: yes, 2008
Presents case studies from Ford's initiative to support efforts to transform universities abroad to enable poor, minority, and otherwise underrepresented students to obtain a university degree.
Irma Rosa Martinez   +4 more
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Investing in Higher Education [PDF]

open access: yes, 2004
Kirby (Noland) Dyess ‘68 learned early on she could do whatever she put her mind ...
Davis, Laura
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Higher education stimulating creative enterprise [PDF]

open access: yes, 2011
This report summarises the research undertaken by the Business & Community School at the University for the Creative Arts (UCA), analysing ways that higher ediucation (HEIs) can support, and indeed stimulate, the creative economy.
Campbell, Frances, Ely, Philip
core   +1 more source

Machine learning in coronary heart disease prediction: Structural equation modelling approach

open access: yesCogent Engineering, 2020
This research is an application of machine learning in medical sciences. The purpose of this research was to use machine learning through the simulated data to study the association of age, body mass index, cigarettes smoked per day, alcohol consumed per
Lewlyn L. R. Rodrigues   +7 more
doaj   +1 more source

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